Department of Neurology, Marcus Stroke & Neuroscience Center, Grady Memorial Hospital, Emory University School of Medicine, Atlanta, GA, USA.
Interv Neuroradiol. 2021 Jun;27(3):427-433. doi: 10.1177/1591019920982219. Epub 2020 Dec 22.
Thromboaspiration technology continues to evolve at an accelerated pace with increasing availability of larger and more navigable devices. Herein, we provide our initial experience with the intracranial navigation of a large-bore (.088" inner diameter) catheters during mechanical thrombectomy (MT).
Retrospective review of consecutive large vessel occlusion stroke patients in whom a TracStar™ or Zoom 88™ (Imperative Care, Campbell, CA) large-bore catheters were utilized in MT. The primary outcome was successful reperfusion (eTICI2b-3) at the end of the procedure. Safety measures included procedural complications and rates of symptomatic intracranial hemorrhage.
Five patients (age,∼50-85 years; baseline NIHSS,17-23) were treated. The .088" catheters were used as the primary tool for contact aspiration in two patients (distal basilar artery and proximal MCA occlusions) with complete thrombus ingestion (eTICI3) during the first pass. In two patients, the .088" catheter was used for flow control where it was placed in the distal M1-segment of a patient with M2 occlusion treated with a combination of stent-retriever and .070" aspiration catheter and in the proximal M1 in a patient with distal M1 occlusion treated with .071" aspiration catheter resulting in eTICI3 reperfusion in both cases. In the fifth patient, the .088" catheter was navigated into the cavernous ICA to support .071" aspiration catheter treatment of an M2 occlusion resulting in eTCI2b67 reperfusion. Procedural duration ranged between 14 and 33 minutes. There were no adverse events.
Intracranial navigation of .088" large-bore catheters in MT appears technically feasible and safe. Larger prospective studies are warranted.
血栓抽吸技术随着更大和更易操控的设备的普及,正以前所未有的速度发展。在此,我们报告在机械取栓(MT)中使用大口径(内径为.088")导管进行颅内导航的初步经验。
回顾性分析连续接受 MT 治疗的大血管闭塞性卒中患者,使用 TracStar™或 Zoom 88™(Imperative Care,加利福尼亚州坎贝尔)大口径导管。主要结局为治疗结束时的成功再灌注(eTICI2b-3)。安全性措施包括手术并发症和症状性颅内出血的发生率。
5 例患者(年龄 50-85 岁;基线 NIHSS 评分 17-23)接受了治疗。在 2 例患者(基底动脉远端和 MCA 近端闭塞)中,将.088"导管用作接触抽吸的主要工具,第一次通过时完全抽吸血栓(eTICI3)。在 2 例患者中,将.088"导管用于血流控制,将其放置在 M2 闭塞患者的 M1 段远端,该患者联合使用支架取栓和.070"抽吸导管治疗,以及在 M1 近端放置于 M1 近端的患者,该患者使用.071"抽吸导管治疗,这两例患者的再灌注均达到 eTICI3。在第 5 例患者中,将.088"导管导航至海绵窦内颈动脉,以支持.071"抽吸导管治疗 M2 闭塞,再灌注达到 eTICI2b67。手术时间为 14-33 分钟。无不良事件发生。
MT 中使用.088"大口径导管进行颅内导航在技术上是可行且安全的。需要进行更大规模的前瞻性研究。