Department of Engineering Sciences and Mathematics, Materials Science, Wood and Bionanocomposites, Luleå University of Technology, 971 87 Luleå, Sweden.
RISE Research Institutes of Sweden, Bioeconomy and Health, Sustainable Materials and Packaging, 114 86 Stockholm, Sweden.
Carbohydr Polym. 2025 Jan 15;348(Pt A):122812. doi: 10.1016/j.carbpol.2024.122812. Epub 2024 Sep 29.
From an economic and environmental perspective, the use of less chemicals in the production of cellulose nanofibrils (CNFs) is advantageous. In this study, we investigated the oxidation (TEMPO/NaClO/NaClO, pH 6.8) of softwood (SW) particles with varying amounts of TEMPO (16, 8 or 0 mg g of wood). Following, TEMPO-oxidized SW nanofibrils (TO-SWNFs) were obtained by nanofibrillation and their size, morphology, and crystallite size were assessed. Hydrogel networks of TO-SWNFs were prepared and mechanical properties were measured in dHO and phosphate buffered saline (PBS) to compare their performance for possible biomedical applications such as wound dressings. The results reveal that the presence of TEMPO is of importance for TO-SWNF network properties, presenting higher eq. HO absorption (≈2500 %) and elongation at break (≈10 %) with good wet strength (≈180 kPa). In addition, a decrease in use of TEMPO catalyst from 16 to 8 mg g of wood is possible, without detrimental effects on hydrogel network properties (dHO absorption ≈ 2000 %, elongation at break ≈ 13 %, wet strength ≈ 190 kPa) related to applications as wound dressings.
从经济和环境的角度来看，在生产纤维素纳米纤维（CNF）时减少化学品的使用是有利的。在这项研究中，我们研究了不同 TEMPO（16、8 或 0mg/g 木材）用量的软木（SW）颗粒的氧化（TEMPO/NaClO/NaClO，pH 6.8）。随后，通过纳米纤维化获得了 TEMPO 氧化的 SW 纳米纤维（TO-SWNF），并评估了它们的尺寸、形态和结晶度。制备了 TO-SWNF 的水凝胶网络，并在 dHO 和磷酸盐缓冲盐水（PBS）中测量了机械性能，以比较它们在可能的生物医学应用中的性能，如伤口敷料。结果表明，TEMPO 的存在对 TO-SWNF 网络性能很重要，表现出更高的平衡水吸收（≈2500%）和断裂伸长率（≈10%），具有良好的湿强度（≈180kPa）。此外，在不影响水凝胶网络性能（dHO 吸收≈2000%，断裂伸长率≈13%，湿强度≈190kPa）的情况下，有可能将 TEMPO 催化剂的用量从 16mg/g 木材减少到 8mg/g 木材，这与伤口敷料等应用有关。
