Guinal Safrollah M, Jamora Roland Dominic G, Khu Kathleen Joy O, Aguilar Jose A
Division of Adult Neurology, Department of Neurosciences, College of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
Section of Neurology, Department of Internal Medicine, Cardinal Santos Medical Center, San Juan City, Philippines.
Neurol Sci. 2025 Mar;46(3):1121-1130. doi: 10.1007/s10072-024-07882-1. Epub 2024 Nov 20.
Magnetic resonance guided focused ultrasound (MRgFUS) is a non-invasive therapeutic technique that utilizes focused ultrasound waves to generate heat at specific tissue targets within the brain. This emerging technology holds promise for its precision and potential benefits in comparison to traditional surgical interventions. This investigation involves a scoping review, summarizing insights from various studies that explore the advantages, limitations, and outcomes associated with MRgFUS in the treatment of dystonia.
This scoping review was conducted using the Preferred Reporting Items for Systematic reviews and Meta-analysis Extension for Scoping Reviews (PRISMA-ScR) guidelines. Data available on MRgFUS use in the management of different types of dystonia were extracted.
There is limited data available (n = 11). In the surveyed literature, MRgFUS has consistently shown clinical benefit in patients with dystonia. It is an emerging avenue of treatment and has its challenges.
This scoping review highlighted the early but encouraging applications of MRgFUS in dystonia management. While data was limited, existing studies consistently demonstrated positive clinical outcomes. The non-invasive and precise nature of MRgFUS positions it as a promising avenue for further research, despite the challenges associated with its emergent status. This review sets the stage for future inquiries, emphasizing its potential as a valuable tool in dystonia treatment.
磁共振引导聚焦超声（MRgFUS）是一种非侵入性治疗技术，利用聚焦超声波在脑内特定组织靶点产生热量。与传统手术干预相比，这项新兴技术因其精准性和潜在益处而具有前景。本调查涉及一项范围综述，总结了各种研究中关于MRgFUS治疗肌张力障碍的优势、局限性和结果的见解。
本范围综述按照系统评价和Meta分析扩展的范围综述首选报告项目（PRISMA-ScR）指南进行。提取了关于MRgFUS用于管理不同类型肌张力障碍的可用数据。
可用数据有限（n = 11）。在所调查的文献中，MRgFUS在肌张力障碍患者中一直显示出临床益处。它是一种新兴的治疗途径，也面临挑战。
本范围综述突出了MRgFUS在肌张力障碍管理中的早期但令人鼓舞的应用。虽然数据有限，但现有研究一致显示出积极的临床结果。MRgFUS的非侵入性和精确性使其成为一个有前景的进一步研究途径，尽管其新兴地位带来了挑战。本综述为未来的研究奠定了基础，强调了其作为肌张力障碍治疗中一种有价值工具的潜力。
