di Biase Lazzaro, Di Santo Alessandro, Caminiti Maria Letizia, Pecoraro Pasquale Maria, Di Lazzaro Vincenzo
Neurology Unit, Campus Bio-Medico University Hospital Foundation, Via Álvaro del Portillo 200, 00128 Rome, Italy.
Unit of Neurology, Neurophysiology, Neurobiology, Department of Medicine, Università Campus Bio-Medico di Roma, Via Álvaro del Portillo 21, 00128 Rome, Italy.
Life (Basel). 2022 Jan 29;12(2):206. doi: 10.3390/life12020206.
Dystonia is a hyperkinetic movement disorder characterized by abnormal movement or posture caused by excessive muscle contraction. Because of its wide clinical spectrum, dystonia is often underdiagnosed or misdiagnosed. In clinical practice, dystonia could often present in association with other movement disorders. An accurate physical examination is essential to describe the correct phenomenology. To help clinicians reaching the proper diagnosis, several classifications of dystonia have been proposed. The current classification consists of axis I, clinical characteristics, and axis II, etiology. Through the application of this classification system, movement disorder specialists could attempt to correctly characterize dystonia and guide patients to the most effective treatment. The aim of this article is to describe the phenomenological spectrum of dystonia, the last approved dystonia classification, and new emerging knowledge.
肌张力障碍是一种运动亢进性运动障碍,其特征是肌肉过度收缩导致异常运动或姿势。由于其临床谱广泛,肌张力障碍常被漏诊或误诊。在临床实践中,肌张力障碍常与其他运动障碍同时出现。准确的体格检查对于描述正确的症状学至关重要。为帮助临床医生做出正确诊断,已提出了几种肌张力障碍的分类方法。目前的分类包括I轴(临床特征)和II轴(病因)。通过应用这一分类系统,运动障碍专家可尝试正确描述肌张力障碍的特征,并指导患者接受最有效的治疗。本文旨在描述肌张力障碍的症状学谱、最新批准的肌张力障碍分类以及新出现的知识。