Deng Ruoqi, Uzuner Sabri, Li L P
Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive, N.W., Calgary, AB, T2N 1N4, Canada.
Department of Mechatronics, Faculty of Engineering, University of Duzce, Konuralp Campus, 81620, Duzce, Marmara, Türkiye.
Sci Rep. 2024 Nov 19;14(1):28595. doi: 10.1038/s41598-024-79662-y.
Finite element modeling has served as a cornerstone in understanding knee joint mechanics post-meniscectomy, yet the influence of varying knee geometries remains unknown. The present study aimed to fill that gap by employing statistical shape modeling to generate knee models from MRI data of 31 human knees, capturing the population's knee size and shape variations. Finite element simulations were conducted to replicate intact, partial, and total medial meniscectomy conditions during standing. The results revealed a substantial shift in load distribution from the medial to lateral compartment following medial meniscectomy with its magnitude depending on knee geometry. Cartilages experienced variable degrees of pressure changes at different sites, which could also be different for fluid and contact pressures. While changes in joint size led to somewhat predictable alterations in contact pressure, variations in joint shape resulted in unexpected changes in contact and fluid pressures, emphasizing the need for computational simulations. The average knee geometry exhibited the lowest contact and fluid pressures under the given loading and boundary conditions, in contrast to knees with shapes deviating from the average. This study highlights the significance of individual knee shape in the biomechanical outcome of meniscectomy, potentially explaining the variability in clinical outcomes observed post-surgery.
有限元建模一直是理解半月板切除术后膝关节力学的基石，但不同膝关节几何形状的影响仍不明确。本研究旨在通过采用统计形状建模，从31个健康人膝关节的MRI数据生成膝关节模型，捕捉人群膝关节大小和形状的变化，来填补这一空白。进行了有限元模拟，以复制站立时完整、部分和完全内侧半月板切除的情况。结果显示，内侧半月板切除术后，负荷分布从内侧间室显著转移到外侧间室，其幅度取决于膝关节的几何形状。软骨在不同部位经历了不同程度的压力变化，流体压力和接触压力也可能不同。虽然关节大小的变化导致接触压力有一定程度的可预测变化，但关节形状的变化导致接触压力和流体压力出现意外变化，这凸显了计算模拟的必要性。在给定的载荷和边界条件下，平均膝关节几何形状的接触压力和流体压力最低，而形状偏离平均值的膝关节则相反。本研究强调了个体膝关节形状在半月板切除术后生物力学结果中的重要性，这可能解释了术后临床结果的变异性。
