Zhang H Y, Tang K Q, Zhang K, Cao H, Li Z P, Zhu W Y
Department of Neonatology, the First People's Hospital of Kunshan, Kunshan215300, China.
Department of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai201102, China.
Zhonghua Er Ke Za Zhi. 2024 Dec 2;62(12):1191-1195. doi: 10.3760/cma.j.cn112140-20240508-00311.
To analyze the ultrasonographic measurements of inferior vena cava (IVC) and abdominal aorta in healthy full-term neonates throughout the early postnatal period. Prospective observational study was conducted. A total of 132 healthy full-term neonates, who were born at the Kunshan First People's Hospital between May 1 and August 30, 2023, were enrolled as the study subjects. Two-dimensional and M-mode ultrasonography were used to measure the maximum and minimum diameters of the IVC and abdominal aorta in the early postnatal period. The IVC collapsibility index, the ratio of maximum IVC diameter to abdominal aorta diameter, and the ratio of minimum IVC diameter to abdominal aorta diameter were calculated. These neonates were stratified by gender, birth mode, gestational age and birth weight (<3 000 or ≥3 000 g), and independent sample -test or Kruskal-Wallis test was used to compare the ultrasonography measurements by different groups. Among the 132 neonates, 81 were males, with a gestational age of (39.2±1.0) weeks, and a birth weight of (3 326±409) g. There were no significant statistical differences in the the maximum and minimum diameters of the IVC and abdominal aorta assessed by both two-dimensional and M-modes between the first and second days (all 0.05). Additionally, no statistical differences were observed in the ultrasonographic measurements among neonates of different sexes, birth modes, and gestational ages (all 0.05); but there were statistically differences between the group with birth weight of <3 000 g and the group with birth weight of ≥3 000 g (all <0.05). There were no statistically differences in IVC collapsibility index, the ratio of the maximum diameter of IVC to the diameter of abdominal aorta, and the ratio of the minimum diameter of IVC to the diameter of abdominal aorta between the group with birth weight of <3 000 g and the group with birth weight of≥3 000 g (all >0.05). The diameters of the IVC and abdominal aorta in healthy full-term neonates during the early postnatal period are correlated with birth weight. The IVC collapsibility index and the ratio of IVC diameter to abdominal aorta diameter are unrelated to birth weight and can be used to assess newborn blood volume or right cardiac preload.
分析健康足月儿出生后早期下腔静脉(IVC)和腹主动脉的超声测量值。进行前瞻性观察研究。选取2023年5月1日至8月30日在昆山市第一人民医院出生的132例健康足月儿作为研究对象。采用二维和M型超声测量出生后早期IVC和腹主动脉的最大和最小直径。计算IVC塌陷指数、IVC最大直径与腹主动脉直径之比以及IVC最小直径与腹主动脉直径之比。将这些新生儿按性别、出生方式、胎龄和出生体重(<3000或≥3000g)分层,采用独立样本t检验或Kruskal-Wallis检验比较不同组的超声测量值。132例新生儿中,男81例,胎龄(39.2±1.0)周,出生体重(3326±409)g。二维和M型测量的IVC和腹主动脉最大和最小直径在出生第1天和第2天之间均无显著统计学差异(均P>0.05)。此外,不同性别、出生方式和胎龄的新生儿超声测量值均无统计学差异(均P>0.05);但出生体重<3000g组与出生体重≥3000g组之间存在统计学差异(均P<0.05)。出生体重<3000g组与出生体重≥3000g组在IVC塌陷指数、IVC最大直径与腹主动脉直径之比以及IVC最小直径与腹主动脉直径之比方面均无统计学差异(均P>0.05)。健康足月儿出生后早期IVC和腹主动脉直径与出生体重相关。IVC塌陷指数及IVC直径与腹主动脉直径之比与出生体重无关,可用于评估新生儿血容量或右心前负荷。