院前急救中的脓毒症管理——越早越好？
Sepsis management in pre-hospital care - the earlier, the better?
作者信息
Lazzarin Taline, Ballarin Raquel Simões, Zornoff Leonardo, Tanni Suzana Erico, Paiva Sergio Alberto Rupp de, Azevedo Paula Schmidt, Minicucci Marcos Ferreira
机构信息
Internal Medicine Department - Botucatu Medical School, São Paulo State University (Unesp), Medical School, Rubião Junior s/n, Botucatu, SP, CEP: 18618-970, Brazil.
出版信息
BMC Emerg Med. 2024 Nov 19;24(1):220. doi: 10.1186/s12873-024-01137-0.
Abstract
Emergency medical services often serve as the initial point of contact for septic patients, offering crucial pre-hospital intervention opportunities. However, the efficacy of pre-hospital interventions remains uncertain. From this perspective, we'll talk about the available evidence of pre-hospital sepsis and septic shock treatment and the barriers to its implementation.
摘要
紧急医疗服务通常是脓毒症患者的第一接触点，提供关键的院前干预机会。然而，院前干预的效果仍不确定。从这个角度来看，我们将讨论院前脓毒症和脓毒性休克治疗的现有证据以及实施这些治疗的障碍。
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本文引用的文献
1
Prehospital Antibiotics Improve Morbidity and Mortality of Emergency Medical Service Patients with Sepsis.院前使用抗生素可改善脓毒症急诊医疗服务患者的发病率和死亡率。
HCA Healthc J Med. 2020 Jun 27;1(3):169-177. doi: 10.36518/2689-0216.1063. eCollection 2020.
2
Effect of prehospital transportation on 24-h fluid volume, a analysis of a multicenter, prospective, observational study on fluid volumes in patients with suspected infection.院前转运对24小时液体量的影响：一项关于疑似感染患者液体量的多中心、前瞻性、观察性研究分析
Front Med (Lausanne). 2022 Dec 21;9:1052071. doi: 10.3389/fmed.2022.1052071. eCollection 2022.
3
Prehospital Time Interval for Urban and Rural Emergency Medical Services: A Systematic Literature Review.城乡紧急医疗服务的院前时间间隔：一项系统文献综述
Healthcare (Basel). 2022 Nov 29;10(12):2391. doi: 10.3390/healthcare10122391.
4
Outcomes Associated With Rural Emergency Department Provider-to-Provider Telehealth for Sepsis Care: A Multicenter Cohort Study.农村急诊科医生间远程医疗治疗脓毒症的结局：一项多中心队列研究。
Ann Emerg Med. 2023 Jan;81(1):1-13. doi: 10.1016/j.annemergmed.2022.07.024. Epub 2022 Oct 15.
5
Prehospital Bundle of Care Based on Antibiotic Therapy and Hemodynamic Optimization Is Associated With a 30-Day Mortality Decrease in Patients With Septic Shock.基于抗生素治疗和血流动力学优化的院前 bundled care 与脓毒性休克患者 30 天死亡率降低相关。
Crit Care Med. 2022 Oct 1;50(10):1440-1448. doi: 10.1097/CCM.0000000000005625. Epub 2022 Jul 28.
6
Prehospital fluid therapy in patients with suspected infection: a survey of ambulance personnel's practice.院前感染患者的液体治疗：对急救人员实践的调查。
Scand J Trauma Resusc Emerg Med. 2022 May 31;30(1):38. doi: 10.1186/s13049-022-01025-1.
7
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.拯救脓毒症运动：2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
8
Prehospital hemodynamic optimisation is associated with a 30-day mortality decrease in patients with septic shock.院前血液动力学优化与脓毒性休克患者 30 天死亡率降低相关。
Am J Emerg Med. 2021 Jul;45:105-111. doi: 10.1016/j.ajem.2021.02.060. Epub 2021 Mar 2.
9
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Acta Anaesthesiol Scand. 2021 Apr;65(4):540-548. doi: 10.1111/aas.13777. Epub 2021 Jan 16.
10
Severe sepsis and septic shock in patients transported by prehospital services versus walk in patients to the emergency department.院前服务转运与自行来诊患者的严重脓毒症和感染性休克患者到急诊科的比较。
Am J Emerg Med. 2021 Jul;45:173-178. doi: 10.1016/j.ajem.2020.08.021. Epub 2020 Aug 19.
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