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回复“需要进行组装指标的实验测量来确定生命的阈值”。

Reply to 'Experimental measurement of assembly indices are required to determine the threshold for life'.

机构信息

Earth and Planets Laboratory, Carnegie Institution for Science, Washington, DC 20015, USA.

Department of Civil and Environmental Engineering and Earth Sciences, Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.

出版信息

J R Soc Interface. 2024 Nov;21(220):20240622. doi: 10.1098/rsif.2024.0622. Epub 2024 Nov 20.

DOI:10.1098/rsif.2024.0622
PMID:39563497
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11576840/
Abstract

We clarify misunderstandings of Walker et al. (Walker 2024 21, 20240367 (doi:10.1098/rsif.2024.0367)) related to studies of the assembly pathways of molecular subunits in minerals. The finding that these subunits have calculated assembly pathways less than approximately 25 informs a central premise of Assembly Theory-that only life can produce numerous copies of molecules with assembly indices above a threshold value. What that threshold value might be, and whether the same value applies to chemical systems as different as organic and inorganic molecules, are questions deserving of additional study.

摘要

我们澄清了对沃克等人(Walker 2024 21, 20240367(doi:10.1098/rsif.2024.0367)))的研究的误解,这些研究涉及到分子亚基在矿物中的组装途径。这些亚基的计算组装途径小于约 25 的发现,为组装理论的一个中心前提提供了信息——只有生命才能产生大量具有高于阈值组装指数的分子。这个阈值可能是多少,以及对于有机和无机分子等不同的化学系统是否适用相同的数值,都是值得进一步研究的问题。

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本文引用的文献

1
Experimentally measured assembly indices are required to determine the threshold for life.为了确定生命的门槛,需要测量实验测定的组装指标。
J R Soc Interface. 2024 Nov;21(220):20240367. doi: 10.1098/rsif.2024.0367. Epub 2024 Nov 20.
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Open-ended versus bounded evolution: Mineral evolution as a case study.开放式进化与有限进化:以矿物进化为例的研究
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Molecular assembly indices of mineral heteropolyanions: some abiotic molecules are as complex as large biomolecules.矿物杂多阴离子的分子组装指数:一些无机分子的复杂性可与大型生物分子相媲美。
J R Soc Interface. 2024 Feb;21(211):20230632. doi: 10.1098/rsif.2023.0632. Epub 2024 Feb 21.
4
Assembly theory explains and quantifies selection and evolution.组装理论解释和量化了选择和进化。
Nature. 2023 Oct;622(7982):321-328. doi: 10.1038/s41586-023-06600-9. Epub 2023 Oct 4.
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Formalising the Pathways to Life Using Assembly Spaces.利用装配空间规范通往生命的途径。
Entropy (Basel). 2022 Jun 27;24(7):884. doi: 10.3390/e24070884.
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Exploring and mapping chemical space with molecular assembly trees.利用分子组装树探索和绘制化学空间
Sci Adv. 2021 Sep 24;7(39):eabj2465. doi: 10.1126/sciadv.abj2465.
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