组装理论解释和量化了选择和进化。

Assembly theory explains and quantifies selection and evolution.

机构信息

School of Chemistry, University of Glasgow, Glasgow, UK.

BEYOND Center for Fundamental Concepts in Science, Arizona State University, Tempe, AZ, USA.

出版信息

Nature. 2023 Oct;622(7982):321-328. doi: 10.1038/s41586-023-06600-9. Epub 2023 Oct 4.

Abstract

Scientists have grappled with reconciling biological evolution with the immutable laws of the Universe defined by physics. These laws underpin life's origin, evolution and the development of human culture and technology, yet they do not predict the emergence of these phenomena. Evolutionary theory explains why some things exist and others do not through the lens of selection. To comprehend how diverse, open-ended forms can emerge from physics without an inherent design blueprint, a new approach to understanding and quantifying selection is necessary. We present assembly theory (AT) as a framework that does not alter the laws of physics, but redefines the concept of an 'object' on which these laws act. AT conceptualizes objects not as point particles, but as entities defined by their possible formation histories. This allows objects to show evidence of selection, within well-defined boundaries of individuals or selected units. We introduce a measure called assembly (A), capturing the degree of causation required to produce a given ensemble of objects. This approach enables us to incorporate novelty generation and selection into the physics of complex objects. It explains how these objects can be characterized through a forward dynamical process considering their assembly. By reimagining the concept of matter within assembly spaces, AT provides a powerful interface between physics and biology. It discloses a new aspect of physics emerging at the chemical scale, whereby history and causal contingency influence what exists.

摘要

科学家一直在努力调和生物进化与物理学所定义的宇宙不变定律。这些定律构成了生命的起源、进化以及人类文化和技术的发展的基础,但它们并不能预测这些现象的出现。进化理论通过选择的视角解释了为什么有些事物存在而有些事物不存在。为了理解没有内在设计蓝图的情况下,物理学如何能够产生多样化的、无限制的形式,我们需要一种新的方法来理解和量化选择。我们提出了组装理论(AT)作为一种框架,它不改变物理学定律,而是重新定义了这些定律作用的“物体”的概念。AT 将物体视为不是点状粒子,而是由其可能形成历史定义的实体。这使得物体在个体或所选单元的明确界限内表现出选择的证据。我们引入了一个称为组装的度量(A),捕捉产生给定物体集合所需的因果程度。这种方法使我们能够将新颖性生成和选择纳入复杂物体的物理学中。它解释了如何通过考虑其组装来通过向前动态过程来描述这些物体。通过在组装空间中重新构想物质的概念,AT 在物理学和生物学之间提供了一个强大的接口。它揭示了物理在化学尺度上出现的一个新方面,即历史和因果偶然性影响着存在的事物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aefb/10567559/a6ef7e058ee6/41586_2023_6600_Fig1_HTML.jpg

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