Fajnzylber Jesse, Patterson William M, Nero Neil, Hernandez Adrian V, Deshpande Abhishek
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
Education Institute, Floyd D. Loop Alumni Library, Cleveland Clinic, Cleveland, OH, USA.
Antimicrob Steward Healthc Epidemiol. 2024 Nov 14;4(1):e202. doi: 10.1017/ash.2024.413. eCollection 2024.
Our systematic review and meta-analysis of 40 studies ( = 3,905,559) identified gastric acid suppressants, recent hospitalization, antibiotic exposure, and certain comorbidities as independent predictors of healthcare-associated infection (HA-CDI) among adult inpatients. Targeted antibiotic stewardship and judicious use of gastric acid suppressants can reduce the incidence of HA-CDI.
我们对40项研究(n = 3,905,559)进行的系统评价和荟萃分析确定,胃酸抑制剂、近期住院、抗生素暴露以及某些合并症是成年住院患者医疗相关感染(HA-CDI)的独立预测因素。有针对性的抗生素管理和合理使用胃酸抑制剂可降低HA-CDI的发生率。