关于无法检测到的重组事件的频率。
On the frequency of undetectable recombination events.
作者信息
Stephens J C
出版信息
Genetics. 1986 Apr;112(4):923-6. doi: 10.1093/genetics/112.4.923.
Abstract
Simple analytical results show that many recombination events occur in such a way as to have no effect on the resultant DNA sequence. The proportion of these undetectable events depends on the population size, mutation rate and recombination rate and is quite large for reasonable values of these quantities. Efforts to estimate recombination rates and frequencies directly from DNA sequence data must, therefore, take this undetectable fraction into account.
摘要
简单的分析结果表明，许多重组事件发生的方式对最终的DNA序列没有影响。这些无法检测到的事件的比例取决于种群大小、突变率和重组率，对于这些数量的合理值来说相当大。因此，直接从DNA序列数据估计重组率和频率的努力必须考虑到这个无法检测到的部分。
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本文引用的文献
1
Statistical properties of the number of recombination events in the history of a sample of DNA sequences.DNA序列样本历史中重组事件数量的统计特性。
Genetics. 1985 Sep;111(1):147-64. doi: 10.1093/genetics/111.1.147.
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