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与子宫平滑肌肉瘤相关的恶性破骨细胞样巨细胞瘤。

Malignant osteoclast-like giant cell tumor associated with a uterine leiomyosarcoma.

作者信息

Pilon V A, Parikh N, Maccera J

出版信息

Gynecol Oncol. 1986 Mar;23(3):381-6. doi: 10.1016/0090-8258(86)90142-3.

DOI:10.1016/0090-8258(86)90142-3
PMID:3957125
Abstract

An unusual case of osteoclast-like giant cell tumor associated with a leiomyosarcoma of the uterus is described. The mononuclear cell component of the giant cell tumor was cytologically malignant and the giant cell tumor was present in a biopsy of vaginal recurrence. The patient expired 17 months after diagnosis with extensive tumor despite surgical and radiation treatment. This is the first report of malignant osteoclast-like giant cell tumor associated with a uterine leiomyosarcoma and only the third report of osteoclast-like giant cell tumor in the uterus.

摘要

本文描述了一例罕见的与子宫平滑肌肉瘤相关的破骨细胞样巨细胞瘤病例。巨细胞瘤的单核细胞成分在细胞学上具有恶性特征,且该巨细胞瘤存在于阴道复发活检标本中。尽管接受了手术和放疗,但患者在诊断后17个月因肿瘤广泛转移而死亡。这是首例关于与子宫平滑肌肉瘤相关的恶性破骨细胞样巨细胞瘤的报告,也是子宫破骨细胞样巨细胞瘤的第三例报告。

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Uterine leiomyosarcomas with osteoclast-like giant cells associated with high expression of RUNX2 and RANKL.富含破骨细胞样巨细胞的子宫平滑肌肉瘤与 RUNX2 和 RANKL 的高表达相关。
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Giant cell tumor of the uterus: case report and response to chemotherapy.子宫巨细胞瘤:病例报告及化疗反应
BMC Cancer. 2007 Mar 14;7:46. doi: 10.1186/1471-2407-7-46.
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伴有破骨细胞样巨细胞的软组织平滑肌肉瘤及肺转移
J Clin Pathol. 1994 Apr;47(4):370-1. doi: 10.1136/jcp.47.4.370.