Ningbo Rehabilitation Hospital, Ningbo, Zhejiang, China.
The First People's Hospital of Wenling, Taizhou, Zhejiang, China.
J Alzheimers Dis. 2024 Nov;102(2):275-294. doi: 10.1177/13872877241289396. Epub 2024 Oct 29.
Alzheimer's disease (AD) is a common neurodegenerative disease characterized by amyloid-β (Aβ) deposition and neurofibrillary tangles formed by high phosphorylation of tau protein. At present, drug therapy is the main strategy of AD treatment, but its effects are limited to delaying or alleviating AD. Recently, non-pharmacologic intervention has attracted more attention, and more studies have confirmed that non-pharmacologic intervention in AD can improve the patient's cognitive function and quality of life. This paper summarizes the current non-pharmacologic intervention in AD, to provide useful supplementary means for AD intervention.
阿尔茨海默病（AD）是一种常见的神经退行性疾病，其特征是淀粉样蛋白-β（Aβ）沉积和由高磷酸化tau 蛋白形成的神经原纤维缠结。目前，药物治疗是 AD 治疗的主要策略，但效果仅限于延缓或缓解 AD。最近，非药物干预引起了更多关注，越来越多的研究证实 AD 的非药物干预可以改善患者的认知功能和生活质量。本文总结了 AD 的当前非药物干预措施，为 AD 的干预提供有用的补充手段。
