Zhang Shengcheng, Du Hejun, Zhang Xingtan, Wang Binzhong
Hubei Key Laboratory of Three Gorges Project for Conservation of Fishes, Chinese Sturgeon Research Institute, China Three Gorges Corporation, Yichang 443100, China.
National Key Laboratory for Tropical Crop Breeding, Shenzhen Branch, Guangdong Laboratory for Lingnan Modern Agriculture, Genome Analysis Laboratory of the Ministry of Agriculture, Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences, Shenzhen 518120, China.
G3 (Bethesda). 2025 Feb 5;15(2). doi: 10.1093/g3journal/jkae277.
Genome assembly errors can have a profound effect on downstream analyses. Collinearity-based Assembly Correction Tool GUI is designed to rectify these errors by leveraging collinearity information between the assembled genome and a reference genome. Collinearity-based Assembly Correction Tool GUI provides a user-friendly interface for visualizing and manually correcting assembly errors. It supports various operations such as insertion, deletion, inversion, and swapping of contigs and chromosomes. The software automatically reclusters, relabels, and redraws the assembly after each modification, ensuring that users can easily track changes. Collinearity-based Assembly Correction Tool GUI is a robust tool designed to efficiently correct large-scale assembly errors in polyploid genomes, featuring advanced collinearity detection capabilities.
基因组组装错误会对下游分析产生深远影响。基于共线性的组装校正工具GUI旨在通过利用组装基因组与参考基因组之间的共线性信息来纠正这些错误。基于共线性的组装校正工具GUI提供了一个用户友好的界面，用于可视化和手动校正组装错误。它支持各种操作，如重叠群和染色体的插入、删除、倒位和交换。每次修改后，该软件会自动对组装进行重新聚类、重新标记和重新绘制，确保用户能够轻松跟踪变化。基于共线性的组装校正工具GUI是一个强大的工具，旨在有效纠正多倍体基因组中的大规模组装错误，具有先进的共线性检测能力。
