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小儿骨肉瘤患者的保肢手术

Limb Salvage Surgery in Pediatric Patients with Osteosarcoma.

作者信息

Niculescu Ștefan Adrian, Grecu Alexandru Florian, Gheonea Cristian, Grecu Dan Cristian

机构信息

PhD Student, University of Medicine and Pharmacy of Craiova, Romania.

Department of Orthopedics, University of Medicine and Pharmacy of Craiova, Romania.

出版信息

Curr Health Sci J. 2024 Jul-Sep;50(3):360-367. doi: 10.12865/CHSJ.50.03.03. Epub 2024 Sep 30.

Abstract

Osteosarcoma, although rare, is acknowledged as the most common primary bone tumor in children and adolescents. Osteosarcoma is a highly malignant osteogenic tumor that can develop in any bone, but commonly develops at the metaphysis of long bones. The positive diagnosis of osteosarcoma is based on the pathology exam, since there are no other specific diagnostic tools, and the patients with osteosarcoma are typically treated by a multidisciplinary team of specialists. The mainstream for the surgical treatment of limb osteosarcoma is the limb salvage surgery, whenever this approach does not compromise the oncological outcomes. A large spectrum of reconstructive surgical procedures is used in various centers, and to date there is no large consensus on recommending one over another. It is often that the practitioner has to decide whether the final impact on the quality of life of the child undergoing endoprosthetic replacement or osteoarticular allograft is better with the subsequent inequality of the length of the limb or the radical approach by amputation is better. Special consideration has to be given on the aspects of psychosocial wellbeing of the patients following the initial surgical intervention.

摘要

骨肉瘤虽然罕见,但被认为是儿童和青少年中最常见的原发性骨肿瘤。骨肉瘤是一种高度恶性的成骨性肿瘤,可发生于任何骨骼,但通常发生在长骨的干骺端。骨肉瘤的确诊基于病理检查,因为没有其他特异性诊断工具,骨肉瘤患者通常由多学科专家团队进行治疗。肢体骨肉瘤手术治疗的主流是保肢手术,只要这种方法不影响肿瘤学治疗效果。不同中心采用了各种各样的重建手术方法,迄今为止,对于推荐哪种方法优于其他方法并没有达成广泛共识。通常情况下,医生必须决定,对于接受假体置换或骨关节异体移植的儿童,肢体长度不等对其生活质量的最终影响与截肢这种根治性方法相比,哪种更好。在首次手术干预后,必须特别考虑患者的心理社会福祉方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1145/11580753/ce9d5cfd64e1/CHSJ-50-03-360-fig1.jpg

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