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痴呆症合并髋部骨折患者手术及非手术治疗结果评估

Assessment of Surgical and Non-surgical Outcomes in Patients with Dementia and Hip Fractures.

作者信息

Bradeanu Andrei Vlad, Bounegru Iulian, Pascu Loredana Sabina, Ciubara Anamaria, Balseanu Tudor Adrian

机构信息

Department of Orthopedy and Traumatology, Saint Apostle Andrew Emergency County Clinical Hospital, Galati, Romania.

Faculty of Medicine and Pharmacy, "Dunărea de Jos" University, Galati, Romania.

出版信息

Curr Health Sci J. 2024 Jul-Sep;50(3):381-391. doi: 10.12865/CHSJ.50.03.05. Epub 2024 Sep 30.

DOI:10.12865/CHSJ.50.03.05
PMID:39574819
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11578367/
Abstract

INTRODUCTION

The aging population is associated with increased osteoporosis and risk of hip fractures. Cognitive decline has recorded exponential increases in the last decades, with the rise in life expectancy.

MATERIAL AND METHODS

We conducted a prospective study on 65 patients over 65 years old associated with dementia and hip fractures. We used pre-and post-treatment variables such as age, type of fracture, type of treatment, Charlson Comorbidity Index (CCI), EQ-5D-5L score, and the Harris hip score (HHS) to assess pain, mobility, and mortality. We performed follow-ups at 6 months, 1 year, 2 years, and 3 years.

RESULTS

Patients with dementia typically arrive at the hospital without any previous analgesic treatment and receive lower doses due to poor pain recognition. The 6-month mortality rate was 48.22% and increased to 78.46% at 3 years. The best survival rates were in patients with bipolar prosthesis and Gamma nails, with a 3-year survival rate of 40% and 50%, respectively.

CONCLUSIONS

Patients with dementia have a higher mortality rate compared to cognitively intact patients and the treatment decisions require a multidisciplinary team and individualized recommendations for each patient, due to high surgical risk in the elderly.

摘要

引言

人口老龄化与骨质疏松症增加及髋部骨折风险相关。在过去几十年中,随着预期寿命的增加,认知能力下降呈指数级增长。

材料与方法

我们对65例65岁以上患有痴呆症和髋部骨折的患者进行了一项前瞻性研究。我们使用治疗前后的变量,如年龄、骨折类型、治疗类型、查尔森合并症指数(CCI)、EQ-5D-5L评分和哈里斯髋关节评分(HHS)来评估疼痛、活动能力和死亡率。我们在6个月、1年、2年和3年进行了随访。

结果

患有痴呆症的患者通常在没有任何先前镇痛治疗的情况下入院,并且由于疼痛识别能力差而接受较低剂量的治疗。6个月死亡率为48.22%,3年时升至78.46%。使用双极假体和伽马钉的患者生存率最高,3年生存率分别为40%和50%。

结论

与认知功能正常的患者相比,患有痴呆症的患者死亡率更高,由于老年人手术风险高,治疗决策需要多学科团队并针对每个患者提供个性化建议。

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本文引用的文献

1
Pain Management in the Postoperative Period for People With Dementia: An Integrative Review.痴呆症患者术后疼痛管理:一项综合综述。
Ann Surg Open. 2023 Jul 5;4(3):e301. doi: 10.1097/AS9.0000000000000301. eCollection 2023 Sep.
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Pre-fracture ambulation capacity, Charlson comorbidity index, and dementia as predictors of functional impairment after bipolar hemiarthroplasty for unstable intertrochanteric fracture. A retrospective analysis in 158 octogenarian patients.
骨折前行走能力、查尔森合并症指数和痴呆作为不稳定型股骨转子间骨折双极半髋关节置换术后功能障碍的预测因素。对158例老年患者的回顾性分析。
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Functional autonomy and 12-month mortality in older adults with proximal femoral fractures in an orthogeriatric setting: risk factors and gender differences.老年髋部骨折患者在矫形骨科环境下的功能自主性和 12 个月死亡率:危险因素和性别差异。
Aging Clin Exp Res. 2023 May;35(5):1063-1071. doi: 10.1007/s40520-023-02378-y. Epub 2023 Mar 9.
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Psychometric evaluation of the Pain Assessment in Advanced Dementia scale in an acute general hospital setting.在急性综合医院环境中,对高级痴呆症疼痛评估量表进行心理计量学评估。
Int J Geriatr Psychiatry. 2022 Dec;37(12). doi: 10.1002/gps.5830.
6
High Charlson Comorbidity Index Score is associated with early fracture-related complication for internal fixation of neck of femur fractures.高 Charlson 共病指数评分与股骨颈骨折内固定术后早期骨折相关并发症相关。
Sci Rep. 2022 Mar 19;12(1):4749. doi: 10.1038/s41598-022-08855-0.
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Predicting life expectancy after geriatric hip fracture: A systematic review.预测老年髋部骨折患者的预期寿命:系统评价。
PLoS One. 2021 Dec 15;16(12):e0261279. doi: 10.1371/journal.pone.0261279. eCollection 2021.
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Pain Assessment for Individuals with Advanced Dementia in Care Homes: A Systematic Review.养老院中晚期痴呆症患者的疼痛评估:一项系统综述。
Geriatrics (Basel). 2021 Oct 19;6(4):101. doi: 10.3390/geriatrics6040101.
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