Eli Lilly and Company, Suzhou, China.
Endocrinology and Metabolism Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.
Front Endocrinol (Lausanne). 2024 Nov 7;15:1470394. doi: 10.3389/fendo.2024.1470394. eCollection 2024.
To describe weight management and perceptions in China.
Data were from the Adelphi Real World Obesity Disease Specific Programme™, a cross-sectional survey between April and July 2022 of physicians managing people with obesity or overweight (PwO) and PwO in real-world clinical practice in China. At data collection, eligible PwO were aged ≥18 years, under weight management and/or had a body mass index (BMI) ≥28 kg/m.
In total, 100 physicians and 801 PwO were enrolled. More than two thirds of PwO (70.7%; 531/751) were not diagnosed with obesity until a BMI ≥30 kg/m. Most PwO (78%; 625/801) were on treatment for at least one obesity-related complication (ORC). Physicians commonly initiated weight loss discussions with PwO who already had an ORC (48.0%; 48/100). According to physicians and PwO, the mean target BMI was set at 25.8 kg/m and 24.3 kg/m, and the mean target percentage weight loss was 19.6% and 23.7%, respectively. Over a median 6.4 months of weight management, the mean percentage weight loss was 4.1%. Few PwO achieved the weight loss target set by their physician (9.9%; 69/695) or themselves (2.0%; 14/696). Most physicians and PwO were unsatisfied with the current weight loss (92.3% [739/801] and 82.0% [650/793], respectively).
These findings suggest that earlier intervention may be needed to address obesity as a disease. Most physicians and PwO recognized the importance of normal weight, but few PwO achieved weight loss targets, which may suggest an unmet need for improved weight management.
描述中国的体重管理和观念。
数据来自 Adelphi 真实世界肥胖疾病特定项目 ™，这是一项在 2022 年 4 月至 7 月期间进行的横断面调查，调查了在中国真实临床实践中管理肥胖或超重（PwO）患者和 PwO 的医生。在数据收集时，符合条件的 PwO 年龄≥18 岁，正在接受体重管理，或 BMI≥28kg/m。
共有 100 名医生和 801 名 PwO 参与了这项研究。超过三分之二的 PwO（70.7%；531/751）直到 BMI≥30kg/m 才被诊断为肥胖。大多数 PwO（78%；625/801）正在接受至少一种肥胖相关并发症（ORC）的治疗。医生通常会与已经患有 ORC 的 PwO 开始减肥讨论（48.0%；48/100）。根据医生和 PwO 的说法，平均目标 BMI 设定为 25.8kg/m 和 24.3kg/m，平均目标体重减轻百分比分别为 19.6%和 23.7%。在平均 6.4 个月的体重管理期间，平均体重减轻百分比为 4.1%。很少有 PwO 达到医生（9.9%；69/695）或自己设定的减肥目标（2.0%；14/696）。大多数医生和 PwO 对当前的减肥效果不满意（92.3%[739/801]和 82.0%[650/793]）。
这些发现表明，可能需要更早的干预来解决肥胖作为一种疾病。大多数医生和 PwO 都认识到正常体重的重要性，但很少有 PwO 达到减肥目标，这可能表明需要改进体重管理以满足未满足的需求。
