Balaji Adhithya N, Balasubramanian Balaji, Tarawneh Bushra A
Internal Medicine, Università Cattolica Del Sacro Cuore, Rome, ITA.
Surgery and Oncology, NMC Specialty Hospital, Abu Dhabi, ARE.
Cureus. 2024 Oct 21;16(10):e72082. doi: 10.7759/cureus.72082. eCollection 2024 Oct.
Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that most commonly arise from the pleura, with peritoneal origin being exceptionally uncommon. We report a case of a 51-year-old male who presented with a large abdominal mass, subsequently diagnosed as a solitary fibrous tumor originating from the peritoneum. Radiological evaluation revealed a well-defined mass with a vascular pedicle supplied by the inferior mesenteric artery, extending from the pelvis to the lower abdomen. Surgical resection of the tumor, including part of the rectosigmoid junction was performed and histopathology confirmed the diagnosis of SFT. Immunohistochemistry (IHC) demonstrated positive staining for CD34, BCL2, and STAT6, supporting the diagnosis. The patient remains disease-free after four years of follow-up. This case contributes to the limited literature on peritoneal SFTs, highlighting the importance of IHC in clinching the diagnosis and of long-term follow-up due to the potential for late recurrence.
孤立性纤维瘤（SFTs）是一种罕见的间叶性肿瘤，最常见于胸膜，起源于腹膜的情况极为罕见。我们报告一例51岁男性患者，其表现为腹部巨大肿块，随后被诊断为起源于腹膜的孤立性纤维瘤。影像学评估显示一个边界清晰的肿块，有一条由肠系膜下动脉供血的血管蒂，从盆腔延伸至下腹部。对肿瘤进行了手术切除，包括部分直肠乙状结肠交界处，组织病理学确诊为SFT。免疫组织化学（IHC）显示CD34、BCL2和STAT6呈阳性染色，支持该诊断。经过四年的随访，患者无疾病复发。该病例丰富了关于腹膜SFTs的有限文献，强调了免疫组织化学在确诊中的重要性以及由于存在晚期复发可能性而进行长期随访的重要性。
