Sandakly Nicolas, El Koubayati Georgio, Issa Lea, Abdallah Rim M, Nasser Selim, Haddad Fady
Department of Internal Medicine, Lebanese University Faculty of Medicine, Beirut, LBN.
Department of Internal Medicine and Clinical Immunology, Lebanese University Faculty of Medicine, Beirut, LBN.
Cureus. 2024 Oct 22;16(10):e72098. doi: 10.7759/cureus.72098. eCollection 2024 Oct.
Lyell syndrome, also known as toxic epidermal necrolysis (TEN), is a rare but life-threatening skin condition, often triggered by certain medications. Antiepileptics, allopurinol, and some nonsteroidal anti-inflammatory drugs are the most common causes. Some antibiotics are also common culprits, although tetracyclines are rarely linked to this condition. We hereby report a case of TEN induced by doxycycline in an 18-year-old girl who was taking the drug for the treatment of acne.
莱尔综合征,又称中毒性表皮坏死松解症(TEN),是一种罕见但危及生命的皮肤病,通常由某些药物引发。抗癫痫药、别嘌醇和一些非甾体抗炎药是最常见的病因。一些抗生素也是常见的罪魁祸首,尽管四环素很少与这种疾病相关。我们在此报告一例18岁女孩因服用强力霉素治疗痤疮而诱发中毒性表皮坏死松解症的病例。