Evers Ymke J, Peters Charlotte M M, Wolffs Petra F G, Horsten Dieuwertje L, Weijzen Chantal, Dukers-Muijrers Nicole H T M, Hoebe Christian J P A
Department of Medical Microbiology, Infectious Diseases & Infection Prevention, National Chlamydia trachomatis Reference Laboratory, Care and Public Health Research Institute (CAPHRI), Maastricht University Medical Center (MUMC+).
Sex Transm Dis. 2025 Apr 1;52(4):255-258. doi: 10.1097/OLQ.0000000000002104. Epub 2024 Nov 21.
Female sex workers (FSWs) have a higher burden of sexually transmitted infections (STI), including Neisseria gonorrhoeae (NG), than the non-sex worker population, mainly due to social vulnerability and work-related factors. This large study evaluated the anatomical site distribution of NG, and specifically the occurrence of single-site pharyngeal NG, among FSWs visiting Dutch STI clinics in the Netherlands.
Coded STI clinic consultations from FSW attending any Dutch STI clinic between 2016 and 2021, in which tests were performed on all 3 anatomical sites, according to the Dutch testing policy for FSW, were included in analyses (n = 22,304). To compare the anatomical site distribution of NG among FSWs with women in general, 15,494 consultations from women who were tested on 3 anatomical sites in clinics that performed standard testing at 3 anatomical sites were used. Descriptive statistics were used to compare the anatomical site distribution of NG and occurrence of single-site pharyngeal NG among FSW and universally tested women.
NG was diagnosed among 3.5% (782 of 22,034) among FSWs and 1.7% (271 of 15,494) among universally tested women ( P < 0.001). Pharyngeal NG was diagnosed among 2.3% of FSWs versus 0.8% of universally tested women ( P < 0.001). Single-site pharyngeal NG was diagnosed in 19.9% (156 of 782) of all NG infections, compared with 14.8% (40 of 271) of NG infections among universally tested women.
The substantial proportion pharyngeal NG and single-site pharyngeal NG among FSW confirms the relevance of pharyngeal testing among this key population for optimal patient management, also in the context of the potential role of pharyngeal NG in antimicrobial resistance.
女性性工作者（FSW）感染性传播感染（STI）的负担高于非性工作者群体，包括淋病奈瑟菌（NG），主要是由于社会脆弱性和与工作相关的因素。这项大型研究评估了荷兰性传播感染诊所中女性性工作者淋病奈瑟菌的解剖部位分布，特别是单部位咽部淋病奈瑟菌的发生情况。
纳入2016年至2021年间在荷兰任何一家性传播感染诊所就诊的女性性工作者的编码性传播感染诊所咨询记录，根据荷兰对女性性工作者的检测政策，这些记录对所有三个解剖部位都进行了检测（n = 22304）。为了比较女性性工作者中淋病奈瑟菌的解剖部位分布与一般女性的情况，使用了在三个解剖部位进行标准检测的诊所中对三个解剖部位进行检测的15494名女性的咨询记录。描述性统计用于比较女性性工作者和普遍检测女性中淋病奈瑟菌的解剖部位分布以及单部位咽部淋病奈瑟菌的发生情况。
女性性工作者中3.5%（22034例中的782例）被诊断为淋病奈瑟菌感染，普遍检测女性中为1.7%（15494例中的271例）（P < 0.001）。女性性工作者中2.3%被诊断为咽部淋病奈瑟菌感染，普遍检测女性中为0.8%（P < 0.001）。所有淋病奈瑟菌感染中，19.9%（782例中的156例）被诊断为单部位咽部淋病奈瑟菌感染，普遍检测女性中淋病奈瑟菌感染的这一比例为14.8%（271例中的40例）。
女性性工作者中相当比例的咽部淋病奈瑟菌和单部位咽部淋病奈瑟菌感染证实了在这一关键人群中进行咽部检测对于优化患者管理的相关性，在咽部淋病奈瑟菌对抗菌素耐药性的潜在作用方面也是如此。
