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病例报告:喉软骨肉瘤的激光与射频消融治疗

Case report: A laser and radiofrequency ablation in a laryngeal chondrosarcoma.

作者信息

Mastronicola Romina, Gil Artur, Barrat Agathe, Kayser Elise, Treffel Mathilde, Dolivet Gilles

机构信息

Institut de Cancérologie de Lorraine, 6 avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France; CRAN, CNRS, UMR 7039, Université de Lorraine, Vandœuvre-lès-Nancy, France.

Institut de Cancérologie de Lorraine, 6 avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.

出版信息

Int J Surg Case Rep. 2024 Dec;125:110611. doi: 10.1016/j.ijscr.2024.110611. Epub 2024 Nov 14.

Abstract

INTRODUCTION AND IMPORTANCE

Chondrosarcoma is a tumor which arises from cartilage, and whose apparition can occur in any site. However, it remains rare in the larynx. Management depends on the grade and the stage of the tumor at the time of the presentation. Here is described the case of a 73-year-old man, who presented with a one-month history of dyspnea due to a low-grade (grade I) laryngeal chondrosarcoma. The tumor was successfully treated through a laser and radiofrequency ablation.

CASE REPORT

A 73-year-old man presented with dyspnea that appeared one month earlier. He underwent clinic examination and CT-scan analysis, which revealed a laryngeal lesion. Histological analysis of the lesion led to the conclusion of a low-grade chondrosarcoma. A non-surgical management was chosen during a multidisciplinary consultation meeting, to preserve laryngeal functions. The patient underwent repeated laser and radiofrequency ablation, to reduce the tumor volume. At present, there is still a mass in the area, but the patient doesn't present any other symptoms. However, he has a close follow up, in order that the signs of an early tumoral evolution are promptly detected.

CLINICAL DISCUSSION

Total laryngectomy is often used for laryngeal chondrosarcoma, but it leads to a complete loss of the laryngeal functions, among which we can quote the speaking. Thereby, it would be better for patients to find other ways of conservative management. Consequently, our case presents the success of laser and radiofrequency ablation in the treatment of a laryngeal chondrosarcoma, which allowed to protect laryngeal functions. Nevertheless, this is a non-curative method showing some limitations but improving surgery outcomes and patient quality of life.

CONCLUSION

This report highlights the importance of quick grading in primary laryngeal chondrosarcoma. In this case, localized low-grade chondrosarcoma was treated without surgery, with a successful outcome thanks to laser and radiofrequency ablation.

摘要

引言与重要性

软骨肉瘤是一种起源于软骨的肿瘤,可发生于任何部位。然而,其在喉部仍较为罕见。治疗方案取决于肿瘤在确诊时的分级和分期。本文描述了一名73岁男性患者的病例,该患者因低度(I级)喉软骨肉瘤出现了一个月的呼吸困难症状。该肿瘤通过激光和射频消融成功治疗。

病例报告

一名73岁男性患者出现了一个月前开始的呼吸困难症状。他接受了临床检查和CT扫描分析,结果显示喉部有病变。对病变进行组织学分析后得出低度软骨肉瘤的结论。在多学科会诊会议上选择了非手术治疗方案,以保留喉部功能。患者接受了多次激光和射频消融,以缩小肿瘤体积。目前,该区域仍有肿块,但患者没有出现任何其他症状。然而,他正在接受密切随访,以便及时发现肿瘤早期进展的迹象。

临床讨论

全喉切除术常用于喉软骨肉瘤,但会导致喉部功能完全丧失,其中包括发声功能。因此,患者最好寻找其他保守治疗方法。因此,我们的病例展示了激光和射频消融治疗喉软骨肉瘤的成功,从而保护了喉部功能。然而,这是一种非根治性方法,存在一些局限性,但改善了手术效果和患者生活质量。

结论

本报告强调了原发性喉软骨肉瘤快速分级的重要性。在本病例中,局限性低度软骨肉瘤未通过手术治疗,借助激光和射频消融取得了成功的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c0c8/11617938/29663809bd5f/gr1.jpg

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