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虚拟规划与三维打印导板在颅缝早闭手术治疗中的应用

Application of Virtual Planning and 3-Dimensional Printing Guide in Surgical Management of Craniosynostosis.

作者信息

Wu Kuan-Lin, Lu Ting-Chen, Lin Tzu-Chin, Chan Chun-Shang, Wu Chieh-Tsai

机构信息

Department of Neurosurgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.

Craniofacial Center, Department of Plastic and Reconstructive Surgery and Craniofacial Research Center, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.

出版信息

World Neurosurg. 2025 Feb;194:123475. doi: 10.1016/j.wneu.2024.11.058. Epub 2024 Dec 8.

Abstract

OBJECTIVE

This study aims to elaborate on the application of virtual surgical planning (VSP) and 3-dimensional printing (3DP) guides in the surgical management of craniosynostosis and compare their surgical outcomes with traditional surgical planning.

METHODS

A retrospective review of patients who underwent cranial vault and cranio-orbital remodeling procedures for craniosynostosis was performed. VSP was accomplished by establishing a 3D model from Digital Imaging and Communications in Medicine format computed tomography data. Patients' skull shapes were adjusted according to the age-matched standard skull; cutting and reconstruction guides were printed using a 3D printer. The change of anthropometric cranial indices, the so-called degree of correction, before and after the operation was evaluated to assess the surgical outcome. The traditional surgical planning group serves as the historical control group, and surgical outcomes were compared among propensity-matched patients in the VSP + 3DP group.

RESULTS

In total, 120 patients with various presentations of craniosynostosis were operated on from 2005 to 2024, and 77 received surgery with VSP + 3DP. There were 35 matched pairs. Both had 17 male patients with similar age and body weight. A greater degree of correction was achieved in the VSP + 3DP group (9.75% vs. 6.36%, P value = 0.016) with less intraoperative blood loss (144.57 mL vs. 296.86 mL, P value < 0.001), shorter operation time (335.23 minutes vs. 348.34 minutes, P value = 0.501), and hospital stay (10.31 days vs. 12.63 days, P value = 0.009).

CONCLUSIONS

With VSP and 3DP guides, precise preoperative planning, efficient intra-operative correction of cranial deformity, and objective surgical outcome assessment are achieved in craniosynostosis operations.

摘要

目的

本研究旨在阐述虚拟手术规划(VSP)和三维打印(3DP)导板在颅缝早闭手术治疗中的应用,并将其手术效果与传统手术规划进行比较。

方法

对接受颅盖和颅眶重塑手术治疗颅缝早闭的患者进行回顾性研究。通过从医学数字成像和通信格式的计算机断层扫描数据建立三维模型来完成虚拟手术规划。根据年龄匹配的标准颅骨调整患者的颅骨形状;使用三维打印机打印切割和重建导板。评估手术前后人体测量颅骨指数的变化,即所谓的矫正程度,以评估手术效果。传统手术规划组作为历史对照组,在虚拟手术规划+三维打印组中对倾向匹配的患者进行手术效果比较。

结果

2005年至2024年,共有120例不同表现的颅缝早闭患者接受手术,其中77例接受了虚拟手术规划+三维打印手术。有35对匹配病例。两组均有17例男性患者,年龄和体重相似。虚拟手术规划+三维打印组的矫正程度更高(9.75%对6.36%,P值=0.016),术中失血量更少(144.57毫升对296.86毫升,P值<0.001),手术时间更短(335.23分钟对348.34分钟,P值=0.501),住院时间更短(10.31天对12.63天,P值=0.009)。

结论

使用虚拟手术规划和三维打印导板,在颅缝早闭手术中可实现精确的术前规划、高效的术中颅骨畸形矫正和客观的手术效果评估。

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