Nishibe Toshiya, Iwasa Tsuyoshi, Kano Masaki, Akiyama Shinobu, Iwahashi Toru, Fukuda Shoji, Koizumi Jun, Nishibe Masayasu
Department of Medical Informatics and Management, Hokkaido Information University, Ebetsu, Japan; Department of Cardiovascular Surgery, Tokyo Medical University, Tokyo, Japan.
Department of Medical Informatics and Management, Hokkaido Information University, Ebetsu, Japan.
Ann Vasc Surg. 2025 Feb;111:170-175. doi: 10.1016/j.avsg.2024.10.009. Epub 2024 Nov 22.
Endovascular aneurysm repair (EVAR) has revolutionized the treatment of abdominal aortic aneurysms by offering a less invasive alternative to open surgery. Understanding the factors that influence patient outcomes, particularly for high-risk patients, is crucial. The aim of this study was to determine whether machine learning (ML)-based decision tree analysis (DTA), a subset of artificial intelligence, could predict patient outcomes by identifying complex patterns in data.
This study analyzed 169 patients who underwent EVAR to identify predictors of short-term mortality (within 3 years) using DTA. Data included 23 variables such as age, gender, nutritional status, comorbidities, and surgical details. The Python 3.7 was used as the programming language, and the scikit-learn toolkit was used to complete the derivation and verification of the decision tree classifier.
DTA identified poor nutritional status as the most significant predictor, followed by chronic kidney disease, chronic obstructive pulmonary disease, and advanced age (octogenarian). The decision tree identified 6 terminal nodes with a risk of short-term mortality ranging from 0% to 79.9%. This model had 68.7% accuracy, 65.7% specificity, and 79.0% sensitivity.
ML-based DTA is promising in predicting short-term mortality after EVAR, highlighting the need for comprehensive preoperative assessment and individualized management strategies.
血管内动脉瘤修复术(EVAR)通过提供一种比开放手术侵入性更小的替代方案,彻底改变了腹主动脉瘤的治疗方式。了解影响患者预后的因素,尤其是高危患者的因素,至关重要。本研究的目的是确定基于机器学习(ML)的决策树分析(DTA)(人工智能的一个子集)是否可以通过识别数据中的复杂模式来预测患者的预后。
本研究分析了169例行EVAR的患者,使用DTA识别短期死亡率(3年内)的预测因素。数据包括年龄、性别、营养状况、合并症和手术细节等23个变量。使用Python 3.7作为编程语言,scikit-learn工具包用于完成决策树分类器的推导和验证。
DTA确定营养状况差是最显著的预测因素,其次是慢性肾病、慢性阻塞性肺疾病和高龄(八十多岁)。决策树识别出6个终端节点,短期死亡风险从0%到79.9%不等。该模型的准确率为68.7%,特异性为65.7%,灵敏度为79.0%。
基于ML的DTA在预测EVAR术后短期死亡率方面很有前景,突出了全面术前评估和个体化管理策略的必要性。