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为血管外科患者实施术前衰弱筛查和优化路径与降低30天再入院率相关。

Implementation of a preoperative frailty screening and optimization pathway for vascular surgery patients is associated with decreased 30-day readmission.

作者信息

Dossabhoy Shernaz S, Manuel Stephanie Rose, Yawary Farishta, Lahiji-Neary Tara, Cheng Nathalie, Cianfichi Lisa, Bagdasarian Ani, George Elizabeth L, Marwell Julianna G, Lee Jason T, Dalman Ronald L, Schmiesing Cliff, Arya Shipra

机构信息

Division of Vascular and Endovascular Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA.

Stanford Health Care, Stanford, CA.

出版信息

J Vasc Surg. 2025 Apr;81(4):965-972.e2. doi: 10.1016/j.jvs.2024.11.018. Epub 2024 Nov 22.

Abstract

OBJECTIVE

Frailty is characterized by decreased physiological reserve and vulnerability to adverse events in the presence of a stressor such as surgery. We prospectively implemented a preoperative frailty screening and optimization pathway for patients undergoing vascular surgery and assessed its impact on postoperative outcomes.

METHODS

As part of an ongoing quality improvement initiative, surgical frailty was assessed prospectively in all patients undergoing inpatient surgery using the Risk Analysis Index (RAI). Baseline data were collected from May to July 2022. Frail patients (RAI score of ≥37) were referred to an anesthesia optimization clinic, nutrition consultation, and case management evaluation in the intervention phase (August 2022 to July 2023). Primary outcomes were postoperative hospital length of stay, 30-day readmission, and 30-day mortality. Secondary outcomes included intensive care unit (ICU) admission, ICU length of stay, discharge disposition, and nonhome discharge. Two-way analyses compared frail vs nonfrail patients and preintervention vs postintervention groups using the Student t test or Wilcoxon rank-sum test for continuous variables and the χ or Fisher's exact test for categorical outcomes.

RESULTS

Of all patients scheduled for elective inpatient vascular surgery procedures at a single institution (n = 225), 216 completed frailty screening (mean age, 72 years; 68.5% male; 54.6% White; mean RAI, 28.9; 18.5% frail). Of these, 15 had surgeries cancelled, and 201 ultimately underwent surgery with 36 (17.9%) identified as frail. Overall, frail patients had significantly longer ICU (median, 4.0 days [intertquartile range (IQR), 2.5-13.5 days] vs median, 2.0 days [IQR, 1-4 days]; P = .001) and hospital length of stay (median, 2.45 days [IQR, 1.51-5.67 days] vs median, 1.23 days [IQR, 1.0-2.1 days]; P = .001), higher nonhome discharge (30.6% vs 4.2%; P < .0001), and higher 30-day readmission (22.2% vs 6.7%; P = .009) compared with nonfrail patients. Comparing preintervention and postintervention groups, the 30-day readmission rates for the overall cohort decreased significantly (from 22.2% to 7.5%; P = .03). Among frail patients, there was a trend toward a reduced hospital length of stay (from 4.73 to 2.14 days), nonhome discharge (from 57.1% to 24.1%), and 30-day readmission (from 42.9% to 17.2%); however, these differences did not reach statistical significance. Overall, the 30-day mortality rate was 1.5% with all three deaths (two frail, one nonfrail) occurring during the postintervention period (0% pre vs 1.7% post; P = 1.0).

CONCLUSIONS

Successful implementation of a preoperative frailty screening and optimization pathway for patients undergoing elective vascular surgery led to a significant decrease in overall 30-day readmission and a trend toward reduced hospital length of stay, nonhome discharge, and 30-day readmission for frail patients. Further expansion to all surgical clinics has the potential to improve quality metrics for the health care system.

摘要

目的

虚弱的特征是生理储备下降,在手术等应激源存在时易发生不良事件。我们前瞻性地为接受血管手术的患者实施了术前虚弱筛查和优化路径,并评估了其对术后结局的影响。

方法

作为一项正在进行的质量改进计划的一部分,使用风险分析指数(RAI)对所有接受住院手术的患者进行前瞻性手术虚弱评估。基线数据于2022年5月至7月收集。在干预阶段(2022年8月至2023年7月),虚弱患者(RAI评分≥37)被转介至麻醉优化门诊、营养咨询和病例管理评估。主要结局为术后住院时间、30天再入院率和30天死亡率。次要结局包括重症监护病房(ICU)入住率、ICU住院时间、出院处置和非家庭出院。采用Student t检验或Wilcoxon秩和检验对连续变量进行两组分析,比较虚弱与非虚弱患者以及干预前与干预后组,采用χ²检验或Fisher精确检验对分类结局进行分析。

结果

在一家机构计划进行择期住院血管手术的所有患者中(n = 225),216例完成了虚弱筛查(平均年龄72岁;68.5%为男性;54.6%为白人;平均RAI为28.9;18.5%为虚弱患者)。其中,15例手术取消,201例最终接受手术,36例(17.9%)被确定为虚弱患者。总体而言,与非虚弱患者相比,虚弱患者的ICU住院时间显著更长(中位数为4.0天[四分位间距(IQR)为2.5 - 13.5天],而非虚弱患者中位数为2.0天[IQR为1 - 4天];P = 0.001),住院时间也更长(中位数为2.45天[IQR为1.51 - 5.67天],而非虚弱患者中位数为1.23天[IQR为1.0 - 2.1天];P = 0.001),非家庭出院率更高(30.6%对4.2%;P < 0.0001),30天再入院率更高(22.2%对6.7%;P = 0.009)。比较干预前和干预后组,整个队列的30天再入院率显著下降(从22.2%降至7.5%;P = 0.03)。在虚弱患者中,住院时间有缩短趋势(从4.73天降至2.14天),非家庭出院率(从57.1%降至24.1%)和30天再入院率(从42.9%降至17.2%);然而,这些差异未达到统计学意义。总体而言,30天死亡率为1.5%,所有三例死亡(两例虚弱患者,一例非虚弱患者)均发生在干预后期间(干预前为0%,干预后为1.7%;P = 1.0)。

结论

成功为接受择期血管手术的患者实施术前虚弱筛查和优化路径,导致总体30天再入院率显著下降,虚弱患者的住院时间、非家庭出院率和30天再入院率有下降趋势。进一步扩展至所有外科诊所有可能改善医疗保健系统的质量指标。

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