Ebong W W
J Pediatr Orthop. 1986 Mar-Apr;6(2):177-81. doi: 10.1097/01241398-198603000-00011.
Pathological fracture of long bones occurred in 26 of 129 (20.2%) consecutive patients with sickle cell disease and osteomyelitis. The 26 patients were in either the first (17 subjects) or second (nine subjects) decade of life. The male:female ratio was 9:4. The fracture was significantly more common in acute than in chronic osteomyelitis (p less than 0.05) and in gram-negative than in staphylococcal infection (p less than 0.0001). Therefore, acute long bone osteomyelitis in young patients with sickle cell disease should be immobilized rigidly early and until sufficient new bone has formed, particularly in young West African boys with whole diaphyseal, gram-negative infection.
在129例镰状细胞病合并骨髓炎的连续患者中，有26例（20.2%）发生了长骨病理性骨折。这26例患者年龄处于第一个十年（17例）或第二个十年（9例）。男女比例为9:4。骨折在急性骨髓炎中比在慢性骨髓炎中更常见（p<0.05），在革兰氏阴性菌感染中比在葡萄球菌感染中更常见（p<0.0001）。因此，镰状细胞病年轻患者的急性长骨骨髓炎应尽早严格固定，直至形成足够的新骨，特别是患有全骨干革兰氏阴性菌感染的西非年轻男孩。
