Pereira D, Andrade M, Moreira A, Caramês J, Pojo M, Freitas F
Faculdade de Medicina Dentária da Universidade de Lisboa Rua Professora Teresa Ambrósio, Cidade Universitária 1600-277 Lisboa, Portugal
Med Oral Patol Oral Cir Bucal. 2025 Jan 1;30(1):e107-e116. doi: 10.4317/medoral.26863.
Oral cancer is a global public health problem. Late diagnosis leads to treatment delays, which consequently result in a worse prognosis and a decrease in the 5-year survival rate. The purpose of this study is to evaluate the oral pathology in a population observed within an oral cancer screening developed in Portugal.
Oral cancer opportunistic screening activities were conducted by the non-profit organization Liga Portuguesa Contra o Cancro ‑ Núcleo Regional do Sul (LPCC-NRS) and data collection occurred between March and December 2022. Participants completed an anonymous questionnaire to collect sociodemographic data and lifestyle habits, followed by a clinical examination of the oral cavity. All individuals classified with oral potentially malignant disorders (OPMD), or suspected lesions of malignant neoplasia were subsequently contacted between January and February 2023 and were questioned about undergoing a biopsy and its respective pathological examination result. Descriptive and analytical statistics were applied.
A total of 2674 participants with a mean age of 57 years were screened. Fordyce granules (16.30%) were the most common non-pathological condition, and hairy tongue (11.04%) was the most frequently observed benign lesion. Leukoplakia (43.58%) was the most common oral potentially malignant disorder. Additionally, histological confirmation was obtained for the presence of 4 oral squamous cell carcinomas (OSCC), representing 0.15% of all population screened.
Although benign pathology is the most frequently found, oral potentially malignant disorders and suspected malignant lesions were identified in 6.3% of participants in these oral cancer screenings. In this regard, we conclude that the oral cancer screening actions developed by LPCC-NRS were effective in identifying positive cases of OPMDs and oral cancer, using an intraoral visual examination of the oral cavity.
口腔癌是一个全球性的公共卫生问题。晚期诊断会导致治疗延迟，进而导致预后更差以及5年生存率降低。本研究的目的是评估在葡萄牙开展的一项口腔癌筛查中所观察人群的口腔病理学情况。
非营利组织葡萄牙抗癌联盟 - 南部地区核（LPCC-NRS）开展了口腔癌机会性筛查活动，数据收集于2022年3月至12月期间进行。参与者完成一份匿名问卷以收集社会人口学数据和生活习惯，随后进行口腔临床检查。所有被归类为口腔潜在恶性疾病（OPMD）或疑似恶性肿瘤病变的个体随后在2023年1月至2月期间被联系，并被询问是否接受活检及其各自的病理检查结果。应用了描述性和分析性统计方法。
共筛查了2674名平均年龄为57岁的参与者。福代斯颗粒（16.30%）是最常见的非病理状况，毛舌（11.04%）是最常观察到的良性病变。白斑（43.58%）是最常见的口腔潜在恶性疾病。此外，经组织学证实存在4例口腔鳞状细胞癌（OSCC），占所有筛查人群的0.15%。
尽管良性病理学情况最为常见，但在这些口腔癌筛查中，6.3%的参与者被发现患有口腔潜在恶性疾病和疑似恶性病变。在这方面，我们得出结论，LPCC-NRS开展的口腔癌筛查行动通过对口腔进行口内视觉检查，有效地识别了OPMD和口腔癌的阳性病例。
