Department of Internal Medicine, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Vet Med Sci. 2025 Jan;11(1):e70121. doi: 10.1002/vms3.70121.
Peste des petits ruminants (PPR) is a disease with high morbidity and mortality in small ruminants. A clinical report of this disease in camels has been made in Iran; however, no accurate information is available about infection with this virus in the camel population of Iran.
This study was designed and conducted to detect any trace of seroconversion in dromedary camels in Iran.
A total of 100 serum samples were collected from a slaughterhouse in Khorasan Razavi Province and analysed using a competitive enzyme-linked immunosorbent assay to detect antibodies against the PPR virus.
The results of this study indicated that the frequency of PPR virus exposure in camels in Khorasan Razavi Province was 3% (3 positive cases out of 100 camels). All the positive cases were female.
The seroconversion without any history of clinical disease among these camels indicated their exposure to the PPR virus in this region and their resistance to clinical disease. The resistance and sensitivity to this disease in camels have yet not been fully determined and require further studies. However, stressful risk factors such as transportation may contribute to the occurrence of clinical forms of PPR in camels. The detection of antibodies against the PPR virus in camels in this study reveals the fact that camels may be considerable contributors to the epidemiology of PPR in Iran.
小反刍兽疫（PPR）是一种在小反刍动物中发病率和死亡率都很高的疾病。伊朗曾有过该病在骆驼中临床报告的记录，但有关该病毒在伊朗骆驼群体中的感染情况，尚无确切信息。
本研究旨在检测伊朗单峰驼中是否存在血清学转换的迹象。
从拉扎维霍拉桑省的一个屠宰场采集了 100 份血清样本，使用竞争酶联免疫吸附试验对其进行分析，以检测针对 PPR 病毒的抗体。
该研究结果表明，拉扎维霍拉桑省骆驼中 PPR 病毒的暴露频率为 3%（100 只骆驼中有 3 个阳性病例）。所有阳性病例均为雌性。
这些骆驼在没有临床疾病史的情况下发生血清学转换，表明它们在该地区接触过 PPR 病毒，并且对临床疾病具有抵抗力。骆驼对这种疾病的抵抗力和敏感性尚未完全确定，需要进一步研究。然而，运输等应激危险因素可能导致 PPR 的临床形式在骆驼中发生。本研究中检测到骆驼针对 PPR 病毒的抗体，这表明骆驼可能在伊朗 PPR 的流行病学中发挥了重要作用。
