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一例因不遵医嘱导致复发性落叶型天疱疮的病例。

A Case of Recurrent Pemphigus Foliaceus Following Noncompliance to Medication.

作者信息

Ali Masab, Ahmad Muhammad Husnain, Imran Ali, Ahmad Uswa, Naseer Ahmad Rehan

机构信息

Department of Dermatology Punjab Medical College Faisalabad Pakistan.

Department of Medicine Tentishev Satkynbai Memorial Asian Medical Institute Kant Kyrgyzstan.

出版信息

Clin Case Rep. 2024 Nov 22;12(11):e9622. doi: 10.1002/ccr3.9622. eCollection 2024 Nov.

DOI:10.1002/ccr3.9622
PMID:39582723
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11583072/
Abstract

Pemphigus foliaceus (PF) is a rare autoimmune blistering disorder requiring consistent immunosuppressive therapy for management. A 66-year-old male with a history of PF presented with worsening blisters and erosions after discontinuing medication. The patient had flaccid bullae and erosions on the face, scalp, chest, and back. Histopathology confirmed PF. Treatment with oral prednisolone, azathioprine, and reinitiation of dexamethasone-cyclophosphamide pulse (DCP) therapy led to disease remission. This case underscores the importance of adherence to immunosuppressive therapy in PF management. It also highlights the role of affordable treatment regimens in ensuring patient compliance and successful outcomes.

摘要

落叶型天疱疮（PF）是一种罕见的自身免疫性水疱性疾病，需要持续的免疫抑制治疗来进行管理。一名有PF病史的66岁男性在停药后出现水疱和糜烂加重。患者面部、头皮、胸部和背部有松弛性大疱和糜烂。组织病理学确诊为PF。口服泼尼松龙、硫唑嘌呤治疗以及重新开始地塞米松-环磷酰胺脉冲（DCP）治疗使疾病缓解。该病例强调了在PF管理中坚持免疫抑制治疗的重要性。它还突出了经济实惠的治疗方案在确保患者依从性和成功治疗结果方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/d53fa0cb9744/CCR3-12-e9622-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/281e7ff2ae34/CCR3-12-e9622-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/e1bde6d794f8/CCR3-12-e9622-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/671ba5ecd57f/CCR3-12-e9622-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/d53fa0cb9744/CCR3-12-e9622-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/281e7ff2ae34/CCR3-12-e9622-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/e1bde6d794f8/CCR3-12-e9622-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/671ba5ecd57f/CCR3-12-e9622-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bfd/11583072/d53fa0cb9744/CCR3-12-e9622-g002.jpg

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