Cao Siyang, Wei Yihao, Yue Yaohang, Wang Deli, Xiong Ao, Yang Jun, Zeng Hui
National & Local Joint Engineering Research Centre of Orthopaedic Biomaterials, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Shenzhen Key Laboratory of Orthopaedic Diseases and Biomaterials Research, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.
Regen Ther. 2024 Nov 8;26:1099-1116. doi: 10.1016/j.reth.2024.10.013. eCollection 2024 Jun.
The introduction of three-dimensional (3D) printing scaffolds has emerged as an effective approach to achieving satisfactory revascularization for bone tissue engineering (BTE). However, there is a notable absence of analytical and descriptive investigations concerning the trajectory, essential research directions, current research scenario, pivotal investigative focuses, and forthcoming perspectives. Hence, the objective of this research is to offer a thorough overview of the advancements achieved in 3D printing structures for vascularized BTE within the last 10 years. Information extracted from the Web of Science repository spans from January 1, 2014, to April 1, 2024. Utilizing advanced analytical instruments, we conducted comprehensive scientometric and visual analyses. The findings underscore the predominant influence of China, representing 59.62 % of the overall publications and playing a pivotal role in shaping research within this field. Notable productivity was evident at various institutions, including Shanghai Jiao Tong University, Chinese Academy of Sciences, and Sichuan University. Wang Jinwu and Wu Chengtie stand out as the most prolific contributors in this domain. The highest number of publications in this area was contributed by the journal . In this study, osteogenesis imperfecta, osteosarcoma, fractures, osteonecrosis, and cartilage diseases were identified as the most significant disorders investigated in this research area. By providing a comprehensive scientometric assessment, this study benefits both experienced researchers and newcomers alike, offering prompt access to essential information and fostering the extraction of innovative concepts within this specific field.
三维(3D)打印支架的引入已成为一种有效的方法,可实现骨组织工程(BTE)令人满意的血管再生。然而,关于其发展轨迹、重要研究方向、当前研究情况、关键研究重点和未来前景,明显缺乏分析性和描述性研究。因此,本研究的目的是全面概述过去10年中用于血管化骨组织工程的3D打印结构所取得的进展。从科学网数据库中提取的信息涵盖2014年1月1日至2024年4月1日。利用先进的分析工具,我们进行了全面的科学计量学和可视化分析。研究结果强调了中国的主导影响,占全部出版物的59.62%,在塑造该领域的研究方面发挥了关键作用。包括上海交通大学、中国科学院和四川大学在内的各机构都有显著的研究成果。王晋武和吴成铁是该领域最多产的贡献者。该领域发表论文数量最多的期刊是 。在本研究中,成骨不全、骨肉瘤、骨折、骨坏死和软骨疾病被确定为该研究领域中研究最多的重要疾病。通过提供全面的科学计量学评估,本研究对经验丰富的研究人员和新手都有益,能迅速获取重要信息,并促进在这一特定领域中提取创新概念。