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机械损伤后钛表面氧化物的动态评估显示，在炎症条件下仅发生部分钝化。

Dynamic assessment of titanium surface oxides following mechanical damage reveals only partial passivation under inflammatory conditions.

作者信息

Kotsakis Georgios A, Xie Li, Siddiqui Danyal A, Daubert Diane, Graham Daniel J, Gil Francisco Javier

机构信息

Rutgers School of Dental Medicine, Newark, NJ USA.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan China.

出版信息

Npj Mater Degrad. 2024;8(1):98. doi: 10.1038/s41529-024-00514-1. Epub 2024 Sep 17.

DOI:10.1038/s41529-024-00514-1
PMID:39583186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11578884/
Abstract

Motivated by clinical problems of titanium implant degradation, we developed a workflow that enabled assessment of surface oxide dynamics as a function of clinical interventions and inflammation conditions. We found that mechanical damage led to decrease of stoichiometric TiO ratio in the passivation oxide film and further resulted in accelerated degradation under inflammatory anaerobic conditions. This method can be employed for the assessment of surface oxides to monitor implant safety.

摘要

受钛植入物降解临床问题的驱动，我们开发了一种工作流程，该流程能够根据临床干预措施和炎症条件评估表面氧化物动力学。我们发现，机械损伤导致钝化氧化膜中化学计量TiO比降低，并进一步导致在炎症厌氧条件下加速降解。该方法可用于评估表面氧化物以监测植入物安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/2cfba6c2489a/41529_2024_514_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/6b2aa54c32f6/41529_2024_514_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/57a6abcbd5f0/41529_2024_514_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/419ff175aec7/41529_2024_514_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/376515856620/41529_2024_514_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/2cfba6c2489a/41529_2024_514_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/6b2aa54c32f6/41529_2024_514_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/57a6abcbd5f0/41529_2024_514_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/419ff175aec7/41529_2024_514_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/376515856620/41529_2024_514_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a15f/11578884/2cfba6c2489a/41529_2024_514_Fig5_HTML.jpg

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Int J Oral Implantol (Berl). 2022 Sep 9;15(3):213-248.
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Modified SHI medium supports growth of a disease-state subgingival polymicrobial community in vitro.改良的 SHI 培养基支持疾病状态下龈下多微生物群落的体外生长。
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J Periodontol. 2021 Apr;92(4):580-591. doi: 10.1002/JPER.20-0186. Epub 2020 Sep 11.
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A wear-resistant TiO nanoceramic coating on titanium implants for visible-light photocatalytic removal of organic residues.在钛植入物上制备一种耐磨的 TiO 纳米陶瓷涂层，用于可见光光催化去除有机残留物。
Acta Biomater. 2019 Oct 1;97:597-607. doi: 10.1016/j.actbio.2019.08.009. Epub 2019 Aug 6.
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