Rizaj Diellor, Kelmendi Artidon
Medical Sciences, University for Business and Technology (UBT), Prishtina, ALB.
Rheumatology, University Clinical Center of Kosovo, Prishtina, ALB.
Cureus. 2024 Oct 25;16(10):e72384. doi: 10.7759/cureus.72384. eCollection 2024 Oct.
The introduction of biologics has improved the management of rheumatoid arthritis (RA), enhancing disease control and quality of life for patients. However, despite these advancements, some individuals still experience distress and depression due to the effects of treatment and concerns about the outcomes of biologic therapy. This study aimed to evaluate the current quality of life, level of distress, and depression among RA patients treated with biologics, which could serve as a basis for intervention. The Quality of Life in Rheumatoid Arthritis Instrument II (QoL-RAII), Kessler Psychological Distress Scale (KPDS), and Beck Depression Inventory (BDI) were used to gather the necessary data. These standardized questionnaires were randomly administered to 100 RA patients undergoing biologic treatment. The data were then tabulated and analyzed using the mean and Pearson r correlation. The study's results revealed a low average quality of life and a very high level of psychological distress among the respondents. Additionally, there was an extreme level of depression observed in RA patients. Furthermore, a significant correlation was found between quality of life and the level of psychological distress among the patients. The findings concluded that RA patients have poor quality of life, experience very high levels of psychological distress, and suffer from extreme depression. The study underscored the urgent need for mental health professionals to provide immediate intervention.
生物制剂的引入改善了类风湿关节炎(RA)的管理,提高了疾病控制水平并提升了患者的生活质量。然而,尽管取得了这些进展,一些患者仍因治疗的影响以及对生物治疗结果的担忧而感到痛苦和抑郁。本研究旨在评估接受生物制剂治疗的RA患者当前的生活质量、痛苦程度和抑郁水平,为干预措施提供依据。使用类风湿关节炎生活质量量表II(QoL - RAII)、凯斯勒心理困扰量表(KPDS)和贝克抑郁量表(BDI)收集必要数据。这些标准化问卷被随机发放给100名正在接受生物治疗的RA患者。然后对数据进行制表,并使用均值和皮尔逊r相关性进行分析。研究结果显示,受访者的平均生活质量较低,心理困扰程度非常高。此外,在RA患者中观察到极度抑郁水平。此外,患者的生活质量与心理困扰程度之间存在显著相关性。研究得出结论,RA患者生活质量差,经历非常高水平的心理困扰,并患有极度抑郁。该研究强调心理健康专业人员迫切需要立即进行干预。