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孕期泛发性毛囊角化病1例罕见病例

A Rare Case of Darier Disease Flaring Up During Pregnancy.

作者信息

Gaikwad Vidya, Patel Jay, Hatwar Himali

机构信息

Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

出版信息

Cureus. 2024 Oct 23;16(10):e72176. doi: 10.7759/cureus.72176. eCollection 2024 Oct.

Abstract

Darier disease (DD), which was also known as keratosis follicularis or Darier-White disease, is an autosomal dominant hereditary illness. The illness typically first manifests in adolescence and progresses as a woman reaches reproductive age. Research on the potential effects of DD on the skin and fetus, especially when it affects the groin and vulva, is insufficient. We report a unique case of multiple folliculitis encompassing the skin of the axilla, breasts, belly, and groin during pregnancy. This condition was associated with recurrent episodes of chronic DD that flared up during each pregnancy and was safely delivered vaginally.

摘要

达里埃病(DD),也称为毛囊角化病或达里埃-怀特病,是一种常染色体显性遗传性疾病。该病通常在青春期首次出现,并在女性达到生育年龄时进展。关于DD对皮肤和胎儿的潜在影响的研究不足,尤其是当它影响腹股沟和外阴时。我们报告了一例独特的病例,一名孕妇腋窝、乳房、腹部和腹股沟皮肤出现多发性毛囊炎。这种情况与每次怀孕期间慢性DD反复发作有关,并且通过阴道安全分娩。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e34e/11584214/2ec163cad1eb/cureus-0016-00000072176-i01.jpg

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