Jaiswal Satvik, Bansal Utkarsh, Rathoria Ekansh, Rathoria Richa, Ahuja Ravindra, Agarwal Anjana
Pediatrics, Hind Institute of Medical Sciences, Barabanki, IND.
Pediatrics, Hind Institute of Medical Sciences, Sitapur, IND.
Cureus. 2024 Oct 24;16(10):e72261. doi: 10.7759/cureus.72261. eCollection 2024 Oct.
Background Vitamin D is an important nutrient for skeletal and extra-skeletal health. Mothers and their neonates are frequently vitamin D deficient. This study aimed to find the association of neonatal vitamin D levels with maternal vitamin D levels at birth. Materials and methods This descriptive-observational study was done on mother-baby dyads at a tertiary center, which included mothers delivering a healthy baby at term gestation. In this study, we reviewed 102 mother-baby dyads. The maternal venous blood and cord blood samples were collected after delivery to determine vitamin D levels. Data collected were maternal socio-demographic variables, weight, height, and neonatal anthropometric variables. The descriptive statistics, chi-square test, and Pearson's R were used for analysis. The significant p-value was <0.05. Results The mean (SD) age and body mass index (BMI) of the mothers were 26.50 (4.04) years and 24.27 (4.06) kg/m, respectively. Vitamin D insufficient levels were reported in 96 (92.2%) mothers and 100 (98%) neonates. The mean (SD) vitamin D levels of the mother and neonate were 16.20 (8.29) and 15.23 (7.06) ng/mL, respectively, and were positively associated (chi-square value 3584.16; Pearson's R-value 0.676; p<0.0001). A significant association was found between maternal age, maternal dressing type, BMI, and neonatal anthropometric variables with both maternal and neonatal vitamin D levels. Conclusion A high prevalence of vitamin D deficiency in both mothers and their neonates was found along with a positive correlation between their vitamin D levels. Diagnostic screenings for vitamin D levels and supplementation during pregnancy should be considered to prevent deficiency in the mother-baby dyad.
维生素D是骨骼和骨骼外健康的重要营养素。母亲及其新生儿经常维生素D缺乏。本研究旨在发现新生儿维生素D水平与出生时母亲维生素D水平之间的关联。
本描述性观察性研究在一家三级中心对母婴二元组进行,其中包括足月分娩健康婴儿的母亲。在本研究中,我们回顾了102对母婴二元组。分娩后采集母亲静脉血和脐带血样本以测定维生素D水平。收集的数据包括母亲的社会人口统计学变量、体重、身高以及新生儿人体测量学变量。使用描述性统计、卡方检验和皮尔逊相关系数进行分析。显著p值<0.05。
母亲的平均(标准差)年龄和体重指数(BMI)分别为26.50(4.04)岁和24.27(4.06)kg/m²。96名(92.2%)母亲和100名(98%)新生儿报告维生素D水平不足。母亲和新生儿的平均(标准差)维生素D水平分别为16.20(8.29)和15.23(7.06)ng/mL,且呈正相关(卡方值3584.16;皮尔逊相关系数值0.676;p<0.0001)。发现母亲年龄、母亲着装类型、BMI以及新生儿人体测量学变量与母亲和新生儿维生素D水平之间存在显著关联。
发现母亲及其新生儿中维生素D缺乏的患病率很高,且他们的维生素D水平呈正相关。应考虑在孕期进行维生素D水平的诊断性筛查和补充,以预防母婴二元组中的维生素D缺乏。