Research Centre for Digital Technologies in Dentistry and CAD/CAM at Danube Private University, 3500 Krems an der Donau, Austria.
Flight Physiological Diagnostics and Research, Center for Aerospace Medicine, 10117 Berlin, Germany.
Med Sci (Basel). 2024 Oct 24;12(4):59. doi: 10.3390/medsci12040059.
This study evaluates the suitability of cerebral oximetry using near-infrared spectroscopy (NIRS) compared to traditional pulse oximetry (SpO2) for measuring cerebral oxygen saturation during hypoxia testing, aiming to enhance safety during flight operations and training. The study included 106 participants aged 18-60 years at the Aerospace Medicine Training Center in Königsbrück. Cerebral oxygen saturation (rSO2) and peripheral oxygen saturation (SpO2) were measured using the INVOS™ 5100C cerebral oximeter and Masimo™ MS5 pulse oximeter, respectively. Measurements were taken at baseline, during hypoxia at 25,000 feet, and post recovery. Data analysis included regression analysis, Bland-Altman plots, and concordance correlation coefficients (CCC). Ethical approval was obtained from the Hannover Medical School. Data from 100 participants were analyzed. Baseline SpO2 was 97.5 ± 1.5%, and baseline rSO2 was 77.25 ± 6.4%. During hypoxia, SpO2 dropped significantly, while rSO2 showed higher values. SpO2 recovered faster than rSO2. Deviations in rSO2 between the right and left sides during hypoxia were minimal. Lin's CCC indicated moderate to substantial concordance. NIRS measurements were more stable and less prone to disturbances, with 95 disruptions in pulse oximetry, 25 of which were potentially critical. NIRS is a reliable method for detecting cerebral oxygen saturation, offering significant advantages over traditional pulse oximetry in stability and reliability during hypoxia testing. NIRS is less error-prone, supporting its use for continuous monitoring in aviation settings and enhancing flight safety by providing more accurate hypoxia detection.
本研究评估了近红外光谱（NIRS）脑氧饱和度测定与传统脉搏血氧饱和度（SpO2）相比在缺氧测试中测量脑氧饱和度的适用性，旨在提高飞行操作和训练期间的安全性。该研究纳入了位于科尼斯堡航空医学培训中心的 106 名年龄在 18-60 岁的参与者。使用 INVOS™ 5100C 脑氧饱和度仪和 Masimo™ MS5 脉搏血氧饱和度仪分别测量脑氧饱和度（rSO2）和外周氧饱和度（SpO2）。在基线、25000 英尺缺氧时和恢复后进行测量。数据分析包括回归分析、Bland-Altman 图和一致性相关系数（CCC）。汉诺威医学院获得了伦理批准。对 100 名参与者的数据进行了分析。基线 SpO2 为 97.5 ± 1.5%，基线 rSO2 为 77.25 ± 6.4%。在缺氧期间，SpO2 显著下降，而 rSO2 显示出更高的值。rSO2 的恢复速度快于 SpO2。缺氧时 rSO2 两侧之间的偏差最小。Lin 的 CCC 表明中度至高度一致性。NIRS 测量更稳定，受干扰的可能性更小，脉搏血氧饱和度仪有 95 次干扰，其中 25 次可能是关键的。NIRS 是一种可靠的检测脑氧饱和度的方法，在缺氧测试中，与传统的脉搏血氧饱和度相比，具有更高的稳定性和可靠性。NIRS 出错的可能性更小，支持在航空环境中进行连续监测，并通过更准确地检测缺氧来提高飞行安全性。
