Bradfield H G, Maynard J P
Anaesthesia. 1979 Nov-Dec;34(10):1032-4. doi: 10.1111/j.1365-2044.1979.tb06254.x.
A case of alveolar proteinosis is reported which was treated by lung lavage. The technique requires a Robertshaw double-lumen tube to isolate each lung. Initial ventilation with 100% oxygen removes lung nitrogen and the first 500 ml of saline occupies part of the functional reserve capacity and is not recovered. Lavage is then continued with 500-ml aliquots until the washings become clear. Monitoring the oxygen--haemoglobin saturation by ear-oximetry showed changes of between 15 and 20%, falling during suction and rising during infusion of lavage fluid. At the end of lavage, gas exchange is severely impaired by retained saline and a variable period of controlled ventilation may be required.
报告了一例采用肺灌洗治疗的肺泡蛋白沉积症病例。该技术需要使用罗伯特肖双腔管来隔离每侧肺。最初用100%氧气通气以清除肺内氮气,最初的500毫升生理盐水占据了部分功能储备容量且无法回收。然后继续以500毫升的等份进行灌洗,直到冲洗液变清。通过耳部血氧饱和度测定法监测氧合血红蛋白饱和度显示变化在15%至20%之间,在抽吸时下降,在注入灌洗液时上升。灌洗结束时,残留的生理盐水会严重损害气体交换,可能需要一段可变的控制通气时间。