对艾哈迈德博士和法鲁奇博士的回应：依库珠单抗与血浆置换治疗儿童抗因子H抗体相关非典型溶血尿毒综合征的比较 - Suppr

Response to Dr Ahmed and Dr Farooqi: Eculizumab versus plasma exchange for pediatric anti-FH antibody-associated atypical hemolytic uremic syndrome.

作者信息

Coccia Paula A, Alconcher Laura F

机构信息

Instituto Universitario Escuela de Medicina del Hospital Italiano de Buenos Aires, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Hospital Interzonal General Dr Jose Penna de Bahia Blanca, Bahía Blanca, Argentina.

出版信息

Pediatr Nephrol. 2025 Apr;40(4):1127. doi: 10.1007/s00467-024-06599-9. Epub 2024 Nov 25.

DOI:10.1007/s00467-024-06599-9

PMID:39585357

Abstract

摘要

相似文献

Response to Dr Ahmed and Dr Farooqi: Eculizumab versus plasma exchange for pediatric anti-FH antibody-associated atypical hemolytic uremic syndrome.对艾哈迈德博士和法鲁奇博士的回应：依库珠单抗与血浆置换治疗儿童抗因子H抗体相关非典型溶血尿毒综合征的比较

Pediatr Nephrol. 2025 Apr;40(4):1127. doi: 10.1007/s00467-024-06599-9. Epub 2024 Nov 25.

Anti-CFH-associated hemolytic uremic syndrome: do we still need plasma exchange?抗补体因子 H 相关性溶血尿毒症综合征：我们仍需要血浆置换吗？

Pediatr Nephrol. 2024 Nov;39(11):3263-3269. doi: 10.1007/s00467-024-06373-x. Epub 2024 Apr 17.

Effect of eculizumab and recombinant human soluble thrombomodulin combination therapy in a 7-year-old girl with atypical hemolytic uremic syndrome due to anti-factor H autoantibodies.依库珠单抗与重组人可溶性血栓调节蛋白联合治疗对一名因抗H因子自身抗体导致非典型溶血尿毒综合征的7岁女童的疗效。

CEN Case Rep. 2014 May;3(1):110-117. doi: 10.1007/s13730-013-0097-7. Epub 2013 Sep 12.

Atypical Hemolytic Uremic Syndrome: A Meta-Analysis of Case Reports Confirms the Prevalence of Genetic Mutations and the Shift of Treatment Regimens.非典型溶血性尿毒症综合征：病例报告的荟萃分析证实基因突变的患病率及治疗方案的转变

Ther Apher Dial. 2018 Apr;22(2):178-188. doi: 10.1111/1744-9987.12641. Epub 2017 Dec 17.

Comparison of outcomes after plasma therapy or eculizumab in pediatric patients with atypical hemolytic uremic syndrome.非典型溶血性尿毒症综合征患儿接受血浆疗法或依库珠单抗治疗后的疗效比较。

Clin Exp Nephrol. 2023 Feb;27(2):161-170. doi: 10.1007/s10157-022-02293-y. Epub 2022 Nov 6.

Plasma exchange combined with eculizumab in the management of atypical hemolytic uremic in pediatric patients: A case report.血浆置换联合依库珠单抗治疗小儿非典型溶血性尿毒症综合征：1例报告

Medicine (Baltimore). 2025 Apr 11;104(15):e42090. doi: 10.1097/MD.0000000000042090.

Eculizumab as first-line treatment for patients with severe presentation of complement factor H antibody-mediated hemolytic uremic syndrome.依库珠单抗作为补体因子H抗体介导的溶血尿毒综合征严重表现患者的一线治疗药物。

Pediatr Nephrol. 2025 Apr;40(4):1041-1047. doi: 10.1007/s00467-024-06530-2. Epub 2024 Oct 9.

Atypical Hemolytic Uremic Syndrome With the p.Ile1157Thr C3 Mutation Successfully Treated With Plasma Exchange and Eculizumab: A Case Report.血浆置换联合依库珠单抗成功治疗伴有p.Ile1157Thr C3突变的非典型溶血尿毒综合征：一例报告

Crit Care Explor. 2019 Apr 17;1(4):e0008. doi: 10.1097/CCE.0000000000000008. eCollection 2019 Apr.

Pharmacological Management of Atypical Hemolytic Uremic Syndrome in Pediatric Patients: Current and Future.儿科患者非典型溶血性尿毒综合征的药物治疗：现状与未来。

Paediatr Drugs. 2023 Mar;25(2):193-202. doi: 10.1007/s40272-022-00555-6. Epub 2023 Jan 13.

Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation.补体基因中的致病性变异与依库珠单抗停药后非典型溶血尿毒症综合征复发的风险。

Clin J Am Soc Nephrol. 2017 Jan 6;12(1):50-59. doi: 10.2215/CJN.06440616. Epub 2016 Oct 31.

本文引用的文献

IPNA clinical practice recommendations on care of pediatric patients with pre-existing kidney disease during seasonal outbreak of COVID-19.国际儿科肾脏病学会（IPNA）关于新冠病毒病（COVID-19）季节性暴发期间患有基础肾脏病的儿科患者护理的临床实践建议

Pediatr Nephrol. 2025 May;40(5):1795-1815. doi: 10.1007/s00467-024-06565-5. Epub 2024 Dec 29.

Re: Vanadium exposure and kidney markers in a pediatric population.关于：儿童群体中的钒暴露与肾脏标志物

Pediatr Nephrol. 2025 May;40(5):1823. doi: 10.1007/s00467-024-06647-4. Epub 2024 Dec 24.

Prompt plasma exchanges and immunosuppressive treatment improves the outcomes of anti-factor H autoantibody-associated hemolytic uremic syndrome in children.促发血浆置换和免疫抑制治疗可改善儿童抗因子 H 自身抗体相关性溶血尿毒综合征的预后。

Kidney Int. 2014 May;85(5):1151-60. doi: 10.1038/ki.2013.373. Epub 2013 Oct 2.

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Response to Dr Ahmed and Dr Farooqi: Eculizumab versus plasma exchange for pediatric anti-FH antibody-associated atypical hemolytic uremic syndrome.

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