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国际儿科肾脏病学会(IPNA)关于新冠病毒病(COVID-19)季节性暴发期间患有基础肾脏病的儿科患者护理的临床实践建议

IPNA clinical practice recommendations on care of pediatric patients with pre-existing kidney disease during seasonal outbreak of COVID-19.

作者信息

Alhasan Khalid A, Raina Rupesh, Boyer Olivia, Koh Jean, Bonilla-Felix Melvin, Sethi Sidharth K, Amer Yasser S, Coccia Paula, Temsah Mohamad-Hani, Exantus Judith, Khan Samina A, Zhong Xuhui, Koch Vera, Duzova Ali, Vasudevan Anil, McCulloch Mignon, Allen Upton, Filler Guido, Montini Giovanni

机构信息

Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Organ Transplant Center of Excellence, King Faisal Specialist Hospital & Research Center, Kidney & Pancreas Health Center, Riyadh, Saudi Arabia.

出版信息

Pediatr Nephrol. 2025 May;40(5):1795-1815. doi: 10.1007/s00467-024-06565-5. Epub 2024 Dec 29.

DOI:10.1007/s00467-024-06565-5
PMID:39733391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11946955/
Abstract

The coronavirus disease 2019 (COVID-19) pandemic, instigated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has profoundly impacted healthcare infrastructures around the globe. While children are usually asymptomatic or have mild symptoms, children with pre-existing kidney conditions require specialized attention. This pivotal report, championed by the International Pediatric Nephrology Association (IPNA), delivers precise and actionable recommendations tailored for pediatric patients with kidney ailments in this pandemic landscape. Central to our findings are rigorous infection control protocols. These are particularly stringent in high-risk zones, emphasizing telehealth's indispensable role, the significance of curtailing in-person consultations, and the imperative of following rigorous guidelines in regions with heightened COVID-19 prevalence. Additionally, the report delves into vaccination approaches for children with kidney issues, highlighting that the choice of vaccine is often governed by regional accessibility and policy frameworks, rather than a universal preference. A notable observation is the potential correlation between COVID-19 vaccines and specific kidney disorders. However, establishing a direct causal link remains elusive. In summary, our research accentuates the critical need for specialized pediatric kidney care during global health crises and reaffirms the continuous research imperative, especially regarding vaccination ramifications.

摘要

由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引发的2019冠状病毒病(COVID-19)大流行,对全球医疗基础设施产生了深远影响。虽然儿童通常无症状或症状轻微,但患有基础肾脏疾病的儿童需要特别关注。这份由国际儿科肾脏病协会(IPNA)支持的关键报告,针对在这一疫情背景下患有肾脏疾病的儿科患者提供了精确且可行的建议。我们研究结果的核心是严格的感染控制方案。这些方案在高风险区域尤为严格,强调远程医疗的不可或缺作用、减少面对面咨询的重要性,以及在COVID-19患病率较高地区遵循严格指南的必要性。此外,该报告深入探讨了患有肾脏问题儿童的疫苗接种方法,强调疫苗的选择通常受地区可及性和政策框架的影响,而非普遍偏好。一个值得注意的发现是COVID-19疫苗与特定肾脏疾病之间可能存在关联。然而,建立直接因果关系仍然难以确定。总之,我们的研究强调了在全球卫生危机期间提供专门儿科肾脏护理的迫切需求,并再次确认了持续进行研究的必要性,特别是关于疫苗接种影响方面的研究。

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From Emergence to Endemicity: A Comprehensive Review of COVID-19.从出现到地方性流行:对新冠病毒病的全面综述
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