Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, P.R. China.
School of Public Health, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, P.R. China.
Mikrochim Acta. 2024 Nov 25;191(12):759. doi: 10.1007/s00604-024-06849-5.
Water-soluble N-doped fluorescent (FL) carbon dots (ACDs) were successfully fabricated hydrothermally using ampicillin sodium as sole precursor. The produced ACDs exhibit satisfactory optical behavior, favorable photostability, and acceptable water solubility. With bright blue emission at 450 nm, the ACDs were utilized for multivariate sensing Fe and Cu based on the synergistic effect of the inner filter effect (IFE) and static quenching with detection limits of 0.31 μM and 0.26 μM, respectively. The practicality of ACDs has been verified by the successful determination of Fe and Cu in real water and living cells. These findings confirm the feasibility of the proposed ACDs as FL sensors for efficient and selective detection of Fe and Cu, which present promising prospects for real-time monitoring these two metal ions in environmental and biological systems.
水相合成的氮掺杂荧光（FL）碳点（ACDs）是通过以氨苄西林钠作为唯一前体制备的。所制备的 ACDs 表现出令人满意的光学性能、良好的光稳定性和可接受的水溶性。由于具有 450nm 处的明亮蓝光发射，因此 ACDs 可用于基于内滤效应（IFE）和静态猝灭协同作用的多变量感测 Fe 和 Cu，其检测限分别为 0.31μM 和 0.26μM。通过成功测定实际水样和活细胞中的 Fe 和 Cu，验证了 ACDs 的实用性。这些发现证实了所提出的 ACDs 作为 FL 传感器用于高效和选择性检测 Fe 和 Cu 的可行性，这为实时监测环境和生物系统中这两种金属离子提供了有前景的方法。
