阻塞性睡眠呼吸暂停与心力衰竭关系的最新进展：叙述性综述。
Up-to-date advance in the relationship between obstructive sleep apnea and heart failure: a narrative review.
机构信息
General Practice Medical Center, West China Hospital, Sichuan University, Chengdu, China.
Department of Otorhinolaryngology Head & Neck Surgery, West China Hospital, Sichuan University, Chengdu, China.
出版信息
Sleep Breath. 2024 Nov 25;29(1):2. doi: 10.1007/s11325-024-03170-6.
PURPOSE
Obstructive sleep apnea (OSA) is recognized as an independent and significant risk factor for various cardiovascular and cerebrovascular conditions, including heart failure (HF). In this review, we explore the impact of OSA on HF, examine shared contributing factors and underlying pathophysiological mechanisms, and assess the treatment options for OSA and their potential therapeutic value in HF patients.
METHODS
Pubmed/MEDLINE were searched through September 2024 to explore the relationship between OSA and HF. The relevant papers included OSA and HF, risk factors of OSA and HF, and the prognosis and treatment of HF patients with OSA.
RESULTS
The results showed that OSA increased the risk of HF. OSA can exacerbate or contribute to the onset of HF in several ways. The application of continuous positive airway pressure (CPAP) and other treatments may benefit HF patients with OSA. Drug therapy has shown promise for treating OSA, extensive multi-center studies remain essential, particularly in patients with both OSA and HF.
CONCLUSION
OSA can exacerbate or contribute to the onset and recurrence of HF in several ways. Further studies should be carried out to explore effective treatments in patients with HF and OSA.
目的
阻塞性睡眠呼吸暂停（OSA）被认为是各种心血管和脑血管疾病的独立且重要的危险因素，包括心力衰竭（HF）。在本综述中，我们探讨了 OSA 对 HF 的影响，研究了共同的致病因素和潜在的病理生理机制，并评估了 OSA 的治疗选择及其在 HF 患者中的潜在治疗价值。
方法
通过 2024 年 9 月在 Pubmed/MEDLINE 上进行检索，以探讨 OSA 与 HF 之间的关系。相关论文包括 OSA 和 HF、OSA 和 HF 的危险因素，以及伴有 OSA 的 HF 患者的预后和治疗。
结果
结果表明，OSA 增加了 HF 的风险。OSA 可以通过多种方式加重或促成 HF 的发生。持续气道正压通气（CPAP）等治疗方法的应用可能对伴有 OSA 的 HF 患者有益。药物治疗在治疗 OSA 方面显示出了一定的前景，但仍需要进行广泛的多中心研究，尤其是在同时患有 OSA 和 HF 的患者中。
结论
OSA 可以通过多种方式加重或促成 HF 的发生和复发。应该进行进一步的研究，以探索 HF 和 OSA 患者的有效治疗方法。
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