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激光间质热疗治疗复发性颅底脊索瘤:病例说明

Laser interstitial thermal therapy for treatment of a recurrent skull base chordoma: illustrative case.

作者信息

Chow William D, Lehman Vance T, Gompel Jamie J Van

机构信息

Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota.

出版信息

J Neurosurg Case Lessons. 2024 Nov 25;8(22). doi: 10.3171/CASE24534.

Abstract

BACKGROUND

The authors applied laser interstitial thermal therapy (LITT) to a recurrent skull base chordoma, which has not been previously described.

OBSERVATIONS

A 63-year-old man was initially diagnosed with an 8-cm destructive clival chordoma, which was aggressively resected endoscopically but recurred despite multiple operations, proton radiation therapy, and chemotherapy. The patient underwent uncomplicated LITT for a subtemporal mass, which palliated the tumor for 10 months. However, it did not ultimately prevent the need for resection, although it may have delayed the surgery.

LESSONS

This case study demonstrates the feasibility and safety of LITT in treating these typically surgically challenging tumors. https://thejns.org/doi/10.3171/CASE24534.

摘要

背景

作者将激光间质热疗(LITT)应用于复发性颅底脊索瘤,此前尚无相关描述。

观察结果

一名63岁男性最初被诊断为8厘米的破坏性斜坡脊索瘤,在内镜下进行了积极切除,但尽管进行了多次手术、质子放射治疗和化疗,肿瘤仍复发。该患者因颞下肿块接受了无并发症的LITT治疗,肿瘤缓解了10个月。然而,尽管它可能推迟了手术,但最终未能避免切除的必要性。

经验教训

本病例研究证明了LITT治疗这些通常具有手术挑战性的肿瘤的可行性和安全性。https://thejns.org/doi/10.3171/CASE24534

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93d7/11605527/f3285572000c/CASE24534_figure_1.jpg

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