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尿道狭窄 - 一般概述:定义、尿道解剖及其在狭窄中的临床应用、流行病学、病因学和尿道重建原则。

Urethral strictures - General aspects: Definition, anatomy of the urethra and its clinical application in stenosis, epidemiology, etiology, and principles of urethral reconstruction.

机构信息

Department of Urology, Foch Hospital, Suresnes, France; UMR1179 Inserm Faculty of Medecine, Versailles Saint-Quentin University, Paris Saclay, 78180 Montigny-le-Bretonneux, France.

Department of Andrology, Urology and Renal Transplantation, University of Lille, Lille, France.

出版信息

Fr J Urol. 2024 Nov;34(11):102720. doi: 10.1016/j.fjurol.2024.102720.

DOI:10.1016/j.fjurol.2024.102720
PMID:39586660
Abstract

BACKGROUND

Urethral strictures are a common and persistent pathology in urology with significant clinical repercussions. Our aim is to provide an overview of the general aspects of this condition.

METHODS

A comprehensive review of the literature from PubMed was conducted covering the period from 2020 to 2023. This was complemented by a synthesis of the latest guidelines from the American, European, and French Urological Associations (AUA, EAU, AFU), as well as references from textbooks.

RESULTS

Urethral stricture is defined by a narrowing of less than 16 French. The urethra is divided into posterior and anterior parts. The prevalence of urethral stricture is approximately 0.9%. The most common location for strictures is the anterior urethra, particularly its bulbar portion in males. The main causes are idiopathic, iatrogenic, traumatic, inflammatory, and infectious. A better understanding of urethral anatomy and histopathology provides a key element. Urethral reconstruction is based on prior urethral rest, detailed analysis of the stricture characteristics, and the use of grafts and flaps.

CONCLUSION

Urethral strictures remain a broad pathology. Their definition and epidemiology have been clarified. They require a thorough understanding of the anatomy, etiologies, and principles of urethral reconstruction to optimize management.

摘要

背景

尿道狭窄是泌尿外科中一种常见且持久的病理,具有重要的临床影响。我们旨在对该病症的一般方面进行概述。

方法

对 2020 年至 2023 年期间 PubMed 上的文献进行全面综述,并综合了美国、欧洲和法国泌尿外科协会(AUA、EAU、AFU)的最新指南以及教科书上的参考文献。

结果

尿道狭窄定义为尿道直径小于 16 法国。尿道分为后段和前段。尿道狭窄的患病率约为 0.9%。最常见的狭窄部位是前尿道,尤其是男性的球部。主要病因包括特发性、医源性、创伤性、炎症性和感染性。更好地了解尿道解剖结构和组织病理学是一个关键要素。尿道重建基于先前的尿道保留、对狭窄特征的详细分析以及移植物和皮瓣的使用。

结论

尿道狭窄仍然是一种广泛的病理。其定义和流行病学已经得到明确。需要深入了解尿道解剖结构、病因和尿道重建原则,以优化管理。

相似文献

1
Urethral strictures - General aspects: Definition, anatomy of the urethra and its clinical application in stenosis, epidemiology, etiology, and principles of urethral reconstruction.尿道狭窄 - 一般概述:定义、尿道解剖及其在狭窄中的临床应用、流行病学、病因学和尿道重建原则。
Fr J Urol. 2024 Nov;34(11):102720. doi: 10.1016/j.fjurol.2024.102720.
2
[Which management for anterior urethral stricture in male? 2021 guidelines from the uro-genital reconstruction urologist group (GURU) under the aegis of CAMS-AFU (Committee of Andrology and Sexual Medicine of the French Association of Urology)].男性前尿道狭窄如何治疗?法国泌尿外科学会男科学与性医学委员会(CAMS-AFU)支持下的泌尿生殖重建泌尿外科医生小组(GURU)2021年指南
Prog Urol. 2021 Dec;31(16):1055-1071. doi: 10.1016/j.purol.2021.07.012. Epub 2021 Oct 5.
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Treatment of strictures of the male anterior urethra: Bulbar urethra.男性前尿道狭窄的治疗:球部尿道。
Fr J Urol. 2024 Nov;34(11):102714. doi: 10.1016/j.fjurol.2024.102714.
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Reconstruction of Membranous Urethral Strictures.膜性尿道狭窄的重建
Curr Urol Rep. 2018 Apr 11;19(6):37. doi: 10.1007/s11934-018-0786-z.
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[Analysis of success rates of uretroplasty for adult male bulbar urethral stricture: A systematic review].[成年男性球部尿道狭窄行尿道成形术成功率的分析:一项系统评价]
Prog Urol. 2017 Feb;27(2):49-57. doi: 10.1016/j.purol.2016.12.003. Epub 2017 Jan 20.
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Double inlay plus ventral onlay buccal mucosa graft for simultaneous penile and bulbar urethral stricture.双重镶嵌加腹侧颊黏膜移植治疗阴茎和球部尿道同时狭窄。
Int Braz J Urol. 2018 Jul-Aug;44(4):838-839. doi: 10.1590/S1677-5538.IBJU.2017.0067.
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[Management of male posterior urethral stenosis following trauma and prostatic treatments, techniques and results].[创伤及前列腺治疗后男性后尿道狭窄的处理:技术与结果]
Fr J Urol. 2024 Nov;34(11):102716. doi: 10.1016/j.fjurol.2024.102716.
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Surgical tips and tricks during urethroplasty for bulbar urethral strictures focusing on accurate localisation of the stricture: results from a tertiary centre.尿道下裂成形术中的手术技巧和窍门,重点是准确定位狭窄部位:来自三级中心的结果。
Eur Urol. 2015 Apr;67(4):764-70. doi: 10.1016/j.eururo.2014.12.029. Epub 2015 Jan 8.
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Treatment of male anterior urethra strictures: Meatus, navicular fossa and penile urethra.男性前尿道狭窄的治疗:尿道口、舟状窝和阴茎尿道。
Fr J Urol. 2024 Nov;34(11):102755. doi: 10.1016/j.fjurol.2024.102755.
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Minimally Invasive Management of Posterior Urethral Stricture/Stenosis with DVIU and Mitomycin C Injection.经尿道双极等离子体汽化电切联合丝裂霉素C注射微创治疗后尿道狭窄/闭锁
Urology. 2024 Jan;183:e317-e319. doi: 10.1016/j.urology.2023.10.006. Epub 2023 Oct 20.

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