• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

女性下生殖道中的病毒：宏基因组研究的系统描述性综述。

Viruses in the female lower reproductive tract: a systematic descriptive review of metagenomic investigations.

机构信息

Laboratory of Virology (LIM-52), Department of Infectious Diseases and Tropical Medicine, Instituto de Medicina Tropical de São Paulo, Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.

Department of Obstetrics and Gynecology, Weill Cornell Medicine, New York, NY, USA.

出版信息

NPJ Biofilms Microbiomes. 2024 Nov 25;10(1):137. doi: 10.1038/s41522-024-00613-6.

DOI:10.1038/s41522-024-00613-6
PMID:39587088
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11589587/
Abstract

The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FRT virome composition, revealing the presence of various viral families and noting significant gaps in knowledge. Understanding interactions between the virome, microbiome, and immune system will provide novel insights for preventing and managing lower genital tract disorders.

摘要

女性下生殖道（FRT）拥有复杂的微生物环境，包括真核和原核病毒（病毒组），但其在健康和疾病中的作用尚未完全阐明。本综述整合了 FRT 病毒组组成的研究结果，揭示了多种病毒家族的存在，并指出了知识上的显著空白。了解病毒组、微生物组和免疫系统之间的相互作用将为预防和管理下生殖道疾病提供新的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/8db0503664a6/41522_2024_613_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/8af5e122c80b/41522_2024_613_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/dbd780a06f0d/41522_2024_613_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/0ff5d4c220e0/41522_2024_613_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/8db0503664a6/41522_2024_613_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/8af5e122c80b/41522_2024_613_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/dbd780a06f0d/41522_2024_613_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/0ff5d4c220e0/41522_2024_613_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bbad/11589587/8db0503664a6/41522_2024_613_Fig4_HTML.jpg

相似文献

1
Viruses in the female lower reproductive tract: a systematic descriptive review of metagenomic investigations.女性下生殖道中的病毒：宏基因组研究的系统描述性综述。
NPJ Biofilms Microbiomes. 2024 Nov 25;10(1):137. doi: 10.1038/s41522-024-00613-6.
2
Healthy and moribund Zhikong scallops () developed different viral communities during a mass mortality event.在一次大规模死亡事件中，健康的和濒死的栉孔扇贝形成了不同的病毒群落。
mSystems. 2025 Jun 17;10(6):e0034225. doi: 10.1128/msystems.00342-25. Epub 2025 May 14.
3
Exploring mosquito virome dynamics within São Paulo Zoo: insights into mosquito-virus-environment interactions.探索圣保罗动物园内蚊子病毒群落动态：深入了解蚊子-病毒-环境相互作用。
Front Cell Infect Microbiol. 2025 Jan 10;14:1496126. doi: 10.3389/fcimb.2024.1496126. eCollection 2024.
4
Unveiling viral diversity and dynamics in mosquitoes through metagenomic analysis in Guizhou Province, China.通过中国贵州省的宏基因组分析揭示蚊子中的病毒多样性和动态变化。
Infect Dis Poverty. 2025 Jun 19;14(1):51. doi: 10.1186/s40249-025-01321-9.
5
Patchy burn severity explains heterogeneous soil viral and prokaryotic responses to fire in a mixed conifer forest.斑驳的烧伤严重程度解释了混交针叶林中土壤病毒和原核生物对火灾的异质反应。
mSystems. 2025 May 14:e0174924. doi: 10.1128/msystems.01749-24.
6
Viruses of free-roaming and hunting dogs in Uganda show elevated prevalence, richness and abundance across a gradient of contact with wildlife.乌干达自由放养和狩猎犬的病毒显示出随着与野生动物接触程度的增加，其流行率、丰富度和丰度均升高。
J Gen Virol. 2024 Jul;105(7). doi: 10.1099/jgv.0.002011.
7
Analysis of the overall development trends and hotspots in the research field of the human gut virome.人类肠道病毒组研究领域的整体发展趋势与热点分析
Virol J. 2025 Jul 5;22(1):224. doi: 10.1186/s12985-025-02856-x.
8
Utilizing Viral Metagenomics to Characterize Pathogenic and Commensal Viruses in Pediatric Patients with Febrile Neutropenia.利用病毒宏基因组学鉴定发热性中性粒细胞减少症患儿的致病性和共生性病毒
Viruses. 2025 Feb 28;17(3):345. doi: 10.3390/v17030345.
9
Virome profiling of Aedes albopictus across urban ecosystems in Guangdong reveals sex-specific diversity.对广东城市生态系统中白纹伊蚊的病毒组分析揭示了性别特异性多样性。
Parasit Vectors. 2025 Jul 7;18(1):264. doi: 10.1186/s13071-025-06872-2.
10
Characterization of the Virome in Mosquitoes Across Distinct Habitats in the Yucatán Peninsula, Mexico.墨西哥尤卡坦半岛不同栖息地蚊子体内病毒群落的特征分析
Viruses. 2025 May 26;17(6):758. doi: 10.3390/v17060758.

引用本文的文献

1
Digital droplet PCR-based detection and quantification of ovine papillomavirus DNA from the vaginal virobiota of healthy mares.基于数字液滴PCR技术检测和定量健康母马阴道病毒群中的绵羊乳头瘤病毒DNA
Sci Rep. 2025 Mar 22;15(1):9951. doi: 10.1038/s41598-025-94279-5.

本文引用的文献

1
A multi-kingdom collection of 33,804 reference genomes for the human vaginal microbiome.一个包含 33804 个参考基因组的多王国集合，用于人类阴道微生物组。
Nat Microbiol. 2024 Aug;9(8):2185-2200. doi: 10.1038/s41564-024-01751-5. Epub 2024 Jun 21.
2
Maternal and neonatal viromes indicate the risk of offspring's gastrointestinal tract exposure to pathogenic viruses of vaginal origin during delivery.母婴病毒组表明分娩期间后代胃肠道暴露于源自阴道的致病病毒的风险。
mLife. 2022 Aug 25;1(3):303-310. doi: 10.1002/mlf2.12034. eCollection 2022 Sep.
3
Ten computational challenges in human virome studies.
人类病毒组研究中的十大计算挑战。
Virol Sin. 2024 Dec;39(6):845-850. doi: 10.1016/j.virs.2024.04.008. Epub 2024 Apr 30.
4
Comparative analysis of the vaginal bacteriome and virome in healthy women living in high-altitude and sea-level areas.高海拔地区与海平面地区健康女性阴道细菌组和病毒组的比较分析。
Eur J Med Res. 2024 Mar 7;29(1):157. doi: 10.1186/s40001-023-01391-1.
5
The vulvar microbiome in lichen sclerosus and high-grade intraepithelial lesions.硬化性苔藓和高级别上皮内病变中的外阴微生物群。
Front Microbiol. 2023 Nov 29;14:1264768. doi: 10.3389/fmicb.2023.1264768. eCollection 2023.
6
Temporal and spatial differences in the vaginal microbiome of Chinese healthy women.中国健康女性阴道微生物组的时空差异。
PeerJ. 2023 Dec 1;11:e16438. doi: 10.7717/peerj.16438. eCollection 2023.
7
Exploring the Human Virome: Composition, Dynamics, and Implications for Health and Disease.探索人类病毒组：组成、动态及其对健康和疾病的影响。
Curr Microbiol. 2023 Nov 25;81(1):16. doi: 10.1007/s00284-023-03537-0.
8
Editorial: Torquetenovirus: predictive biomarker or innocent bystander in pathogenesis.社论：细小病毒B19：发病机制中的预测生物标志物还是无辜旁观者？
Front Med (Lausanne). 2023 Sep 27;10:1283454. doi: 10.3389/fmed.2023.1283454. eCollection 2023.
9
Relationship between Human Papillomavirus Status and the Cervicovaginal Microbiome in Cervical Cancer.宫颈癌中人乳头瘤病毒状态与宫颈阴道微生物群的关系
Microorganisms. 2023 May 27;11(6):1417. doi: 10.3390/microorganisms11061417.
10
Microbiome analysis of Brazilian women cervix reveals specific bacterial abundance correlation to RIG-like receptor gene expression.巴西女性宫颈微生物组分析显示特定细菌丰度与 RIG-like 受体基因表达相关。
Front Immunol. 2023 Apr 25;14:1147950. doi: 10.3389/fimmu.2023.1147950. eCollection 2023.