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为英国早发性2型糖尿病患者设计一项区域临床服务。

Designing a regional clinical service for people with early-onset type 2 diabetes in England.

作者信息

Goldney Jonathan, Alabraba Victoria, Sarkar Priscilla, Morgan Harriet, Hamza Malak, Skarlatos Michael, Slater Tommy, Sargeant Jack A, O'Callaghan Rhys, Hadjiconstantinou Michelle, Burdon Julia, Farooqi Azhar, Seidu Samuel, Meek Claire, Davies Melanie J

机构信息

Diabetes Research Centre, University of Leicester, Leicester, UK.

National Institute for Health Research (NIHR) Leicester Biomedical Research Centre, Leicester, UK.

出版信息

Diabet Med. 2025 Apr;42(4):e15479. doi: 10.1111/dme.15479. Epub 2024 Nov 25.

Abstract

AIMS

To design a regional clinical service for people with early-onset type 2 diabetes (EOT2D) in Leicester, Leicestershire and Rutland (England).

METHODS

A literature search was undertaken to identify important considerations. A working group of key stakeholders was formed to design a triage system and service pathway. Electronic medical records (EMRs) were searched (15th November 2023) to assess feasibility of the pathway and adapt accordingly.

RESULTS

A literature search identified important considerations: High risk of complications; large proportion from minority ethnic and socioeconomically deprived backgrounds; significant psychological burden; stigma and other social challenges; and misclassification and miscoding. Novel clinical risk criteria were developed, implementable in EMRs, to match intervention-intensity to clinical need. Specialist clinics were planned, one for people at the highest-clinical risk, another for women with adverse perinatal risk factors. A healthcare professional training package was developed to increase awareness of the unmet clinical needs of people with EOT2D and to upskill in provision of holistic care. Subsequent EMR searches supported the need for our service. Due to the large numbers with HbA1c ≥86mmol/mol (10.0%; n=299; 10.8% of total), these people were prioritised for clinic access. We opted for specialist nurse/educator support to practices with clustering of patients and to financially incentivise referrals from primary care into services.

CONCLUSIONS

We showcase a service specifically for people with EOT2D based on the literature, a broad range of stakeholder involvement and utilising a locally-sourced data-driven approach. We further discuss areas for development and recommendations based on the challenges we encountered.

摘要

目的

为莱斯特、莱斯特郡和拉特兰(英国)的早发型2型糖尿病(EOT2D)患者设计一项区域临床服务。

方法

进行文献检索以确定重要的考虑因素。成立了一个由关键利益相关者组成的工作组,以设计一个分诊系统和服务路径。检索电子病历(2023年11月15日)以评估该路径的可行性并相应进行调整。

结果

文献检索确定了重要的考虑因素:并发症风险高;很大一部分来自少数族裔和社会经济贫困背景;心理负担重;耻辱感和其他社会挑战;以及错误分类和编码错误。制定了可在电子病历中实施的新临床风险标准,以使干预强度与临床需求相匹配。计划设立专科诊所,一个针对临床风险最高的人群,另一个针对有不良围产期风险因素的女性。开发了一个医疗保健专业人员培训包,以提高对EOT2D患者未满足的临床需求的认识,并提升提供整体护理的技能。随后的电子病历检索支持了我们提供服务的必要性。由于糖化血红蛋白≥86mmol/mol的人数众多(10.0%;n = 299;占总数的10.8%),这些人被优先安排进入诊所。我们选择由专科护士/教育工作者为患者聚集的医疗机构提供支持,并在经济上激励初级保健机构将患者转诊至相关服务。

结论

我们展示了一项专门为EOT2D患者设计的服务,该服务基于文献、广泛的利益相关者参与并采用本地数据驱动的方法。我们还根据遇到的挑战讨论了发展领域和建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8000/11929562/9ca4a3f76de4/DME-42-e15479-g001.jpg

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