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甲状腺切除术的完成趋势与比率:一项系统评价和荟萃分析

Completion Thyroidectomy Trends and Rates: A Systematic Review and Meta-Analysis.

作者信息

Soibelman Daniel, Ronen Ohad

机构信息

Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.

Department of Otolaryngology - Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel.

出版信息

Clin Otolaryngol. 2025 Mar;50(2):205-219. doi: 10.1111/coa.14262. Epub 2024 Nov 26.

DOI:10.1111/coa.14262
PMID:39587912
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11792430/
Abstract

BACKGROUND

In January 2016, the American Thyroid Association (ATA) published an update to the guidelines concerning the management of adult patients with thyroid nodules and well-differentiated thyroid cancers. One of the revised recommendations states that lobectomy is a reasonable surgical approach for low-risk patients. This systematic review compares the rates of completion thyroidectomy surgeries before and after the publication of the recent ATA guidelines.

METHODS

A systematic review was conducted according to the PRISMA guidelines of the preferred reporting items for systematic reviews and meta-analyses. PubMed and Embase databases were searched to find articles which demonstrate the rates of completion thyroidectomy surgeries in the last 6 years, before and after the recent ATA guidelines publication. Overall, 8744 titles and abstracts were screened, and 964 articles were fully assessed for eligibility. Eventually, 40 studies were included for data extraction. More than 48 000 patients with thyroid malignancy were included in the review, and were divided into three time periods according to the publication date of 2015 ATA guidelines.

RESULTS

We found that the rate of completion thyroidectomy was 51.8% before 2016 and 43.1% after the 2015 ATA guidelines publication. We observed a 17% reduction of early completion thyroidectomy surgeries since the 2015 ATA guidelines publication relative to previous periods, among patients with malignant pathology.

CONCLUSIONS

Apparently, more centres worldwide implemented the new guidelines and prefer a conservative surgical approach as compared to the pre-ATA 2015 era.

摘要

背景

2016年1月,美国甲状腺协会(ATA)发布了关于成人甲状腺结节和分化型甲状腺癌管理指南的更新版。修订后的建议之一指出,对于低风险患者,甲状腺叶切除术是一种合理的手术方法。本系统评价比较了近期ATA指南发布前后甲状腺全切术的手术率。

方法

根据系统评价和荟萃分析的首选报告项目(PRISMA)指南进行系统评价。检索PubMed和Embase数据库,以查找显示近期ATA指南发布前后过去6年中甲状腺全切术手术率的文章。总共筛选了8744个标题和摘要,并对964篇文章进行了资格全面评估。最终,纳入40项研究进行数据提取。该评价纳入了超过48000例甲状腺恶性肿瘤患者,并根据2015年ATA指南的发布日期将其分为三个时间段。

结果

我们发现,2016年前甲状腺全切术的手术率为51.8%,2015年ATA指南发布后为43.1%。我们观察到,自2015年ATA指南发布以来,在有恶性病理的患者中,早期甲状腺全切术的手术率相对于之前的时期降低了17%。

结论

显然,与2015年ATA之前的时代相比,全球更多的中心实施了新指南,并倾向于采用保守的手术方法。

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Clin Otolaryngol. 2025 Mar;50(2):205-219. doi: 10.1111/coa.14262. Epub 2024 Nov 26.
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The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.PRISMA 2020 声明:系统评价报告的更新指南。
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Case for staged thyroidectomy.分期甲状腺切除术病例。
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Completion Thyroidectomy is Less Common Following Updated 2015 American Thyroid Association Guidelines.根据 2015 年更新的美国甲状腺协会指南,完成甲状腺切除术的情况较少见。
Ann Surg Oncol. 2021 Jan;28(1):484-491. doi: 10.1245/s10434-020-08709-x. Epub 2020 Jun 24.
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Impact of Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclear Features on Revised Bethesda System Malignancy Rates at a Single Institution.具有乳头状核特征的非侵袭性滤泡性甲状腺肿瘤对单一机构修订的贝塞斯达系统恶性率的影响
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Head Neck. 2020 Sep;42(9):2257-2266. doi: 10.1002/hed.26159. Epub 2020 Apr 10.
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Malignancy Rate in Thyroid Nodules with Atypia or Follicular Lesion of Undetermined Significance.具有非典型性或意义未明的滤泡性病变的甲状腺结节的恶性率
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The risk of thyroid carcinoma in multinodular goiter compared to solitary thyroid nodules: A retrospective analysis of 600 patients.多结节性甲状腺肿与孤立性甲状腺结节相比患甲状腺癌的风险:600例患者的回顾性分析
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