Deshmukh Vinit N, Patil Satish, Hinge Dilip D
Department of Molecular Biology and Genetics, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, IND.
Department of Microbiology, Krishna Institute of Medical Sciences, Karad, IND.
Cureus. 2024 Oct 26;16(10):e72435. doi: 10.7759/cureus.72435. eCollection 2024 Oct.
Human papillomavirus (HPV) is a widespread viral infection affecting the reproductive tract and is associated with multiple types of cancer. It is a significant global health concern, with cervical cancer being one of the most common cancers affecting women worldwide. HPV infection has been found in both married and unmarried women. The burden of cervical cancer is particularly high in middle- and low-income countries, where HPV vaccination and screening programs are often limited. India faces a substantial challenge with cervical cancer and HPV infection. Cervical cancer ranks as one of the leading cancers among women in India. Studies over recent decades have indicated varying levels of HPV prevalence in the general female population in India. Recognizing the importance of addressing this issue, the Government of India has prioritized cervical cancer elimination as a national public health goal. A strategic plan has been launched to increase cervical cancer screening coverage in adult women and HPV vaccination coverage in girls. This review examines literature published from 2000 to 2023 on the epidemiology of cervical cancer and HPV in India. It also explores the development of prevention strategies, focusing on cervical screening and HPV vaccination programs. Government policy documents were analyzed to understand the national strategic vision and targets. The review concludes by discussing ongoing challenges and future directions for cervical cancer elimination efforts in India.
人乳头瘤病毒（HPV）是一种广泛传播的病毒感染，影响生殖道，并与多种癌症相关。它是一个重大的全球健康问题，宫颈癌是全球影响女性的最常见癌症之一。已婚和未婚女性中均发现有HPV感染。在中低收入国家，宫颈癌负担尤其沉重，这些国家的HPV疫苗接种和筛查项目往往有限。印度在宫颈癌和HPV感染方面面临巨大挑战。宫颈癌是印度女性中的主要癌症之一。近几十年来的研究表明，印度普通女性人群中HPV流行程度各不相同。认识到解决这一问题的重要性，印度政府已将消除宫颈癌作为国家公共卫生目标的优先事项。已启动一项战略计划，以提高成年女性宫颈癌筛查覆盖率和女童HPV疫苗接种覆盖率。本综述考察了2000年至2023年期间发表的关于印度宫颈癌和HPV流行病学的文献。它还探讨了预防策略的发展，重点是宫颈癌筛查和HPV疫苗接种项目。对政府政策文件进行了分析，以了解国家战略愿景和目标。综述最后讨论了印度消除宫颈癌努力中当前面临的挑战和未来方向。
