Laboratorio de Histología y Embriología Descriptiva, Experimental y Comparada (LHYEDEC), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata (UNLP), La Plata, Buenos Aires, Argentina.
Centro de Estudios Parasitológicos y Vectores (CEPAVE), Consejo Nacional de Investigaciones Científicas y Técnicas, UNLP (CCT, CONICET-UNLP), La Plata, Buenos Aires, Argentina.
Parasitol Res. 2024 Nov 26;123(11):395. doi: 10.1007/s00436-024-08420-w.
Yellow grub disease is a parasite infection, caused by Clinostomum spp. Metacercariae and affecting axial muscles and internal organs of freshwater fish. Killifishes live in seasonal ponds and are short-lived; in the Neotropical region they are among the most vulnerable vertebrates. The current study analyzes the possible injury and inflammatory reaction caused by parasitic infection with Clinostomum spp. metacercariae in testes, ovaries, liver, intestine and mesentery in the seasonal killifishes Trigonectes aplocheiloides and Titanolebias monstrosus. Apparently, this parasite could migrate through the circulatory system to different organs, since a cercaria was found in the lumen of a hepatic sinusoid. In all organs the inflammatory response showed dilated, congested vascular areas and infiltration of numerous inflammatory cells, mainly composed of lymphocytes, eosinophilic granular cells and macrophages. However, the most affected organs were the pancreas, ovaries and testes. In these organs, severe pancreatitis with degranulation of the pancreatic acini, scarce ovarian follicles and spermatocysts dilated with few or no seminiferous cells were observed. In seasonal killifish, yellow grub disease could cause low fertility rates or even sterility by reducing or impairing their reproductive capacity. Therefore, this type of parasitism has a considerable impact on the perpetuation of this species due to the short periods they have to breed before their habitats dry out.
黄颡鱼病是一种寄生虫感染，由 Clino stomum spp. 囊蚴引起，影响淡水鱼类的轴向肌肉和内部器官。食蚊鱼生活在季节性池塘中，寿命短暂；在新热带地区，它们是最脆弱的脊椎动物之一。本研究分析了寄生性感染 Clinostomum spp. 囊蚴对季节性食蚊鱼 Trigonectes aplocheiloides 和 Titanolebias monstrosus 的睾丸、卵巢、肝脏、肠道和肠系膜可能造成的损伤和炎症反应。显然，这种寄生虫可以通过循环系统迁移到不同的器官，因为在肝窦腔的管腔中发现了一个尾蚴。在所有器官中，炎症反应显示出扩张、充血的血管区域和大量炎症细胞的浸润，主要由淋巴细胞、嗜酸性粒细胞和巨噬细胞组成。然而，受影响最严重的器官是胰腺、卵巢和睾丸。在这些器官中，观察到严重的胰腺炎，胰腺腺泡脱颗粒，卵巢卵泡稀少，精囊扩张，只有少数或没有精原细胞。在季节性食蚊鱼中，黄颡鱼病可能通过降低或损害其繁殖能力导致低生育力甚至不育。因此，由于它们在栖息地干涸之前繁殖的时间很短，这种寄生虫对该物种的延续有相当大的影响。
