肾功能评估公式对德国非瓣膜性心房颤动患者在现实生活中使用新型口服抗凝药及正确给药剂量的影响。 - Suppr

Impact of Renal Function Estimation Formulae on Use and Correct Dosing of NOACs in Patients with Non-valvular Atrial Fibrillation in Real Life in Germany.

作者信息

Zeymer Uwe, Riemer Thomas, Wolf Ulrich, Schaefer Steffen, Taggeselle Jens, Kabitz Hans-Joachim, Prondzinsky Roland, Süselbeck Tim, Kleemann Thomas, Zahn Ralf, Heer Tobias

机构信息

Klinikum Ludwigshafen, Medizinische Klinik B, Bremserstrasse 79, 67063, Ludwigshafen, Germany.

Institut für Herzinfarktforschung Ludwigshafen, Ludwigshafen, Germany.

出版信息

Am J Cardiovasc Drugs. 2025 Mar;25(2):287-291. doi: 10.1007/s40256-024-00700-1. Epub 2024 Nov 26.

DOI:10.1007/s40256-024-00700-1

PMID:39589707

Abstract

摘要

相似文献

Impact of Renal Function Estimation Formulae on Use and Correct Dosing of NOACs in Patients with Non-valvular Atrial Fibrillation in Real Life in Germany.肾功能评估公式对德国非瓣膜性心房颤动患者在现实生活中使用新型口服抗凝药及正确给药剂量的影响。

Am J Cardiovasc Drugs. 2025 Mar;25(2):287-291. doi: 10.1007/s40256-024-00700-1. Epub 2024 Nov 26.

Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation.更新的欧洲心脏节律协会实用指南：非维生素 K 拮抗剂抗凝剂在非瓣膜性心房颤动患者中的应用。

Europace. 2015 Oct;17(10):1467-507. doi: 10.1093/europace/euv309. Epub 2015 Aug 31.

Appropriate Dosing Regimens of Non-Vitamin K Antagonist Oral Anticoagulants for Treatment of Patients With Non-Valvular Atrial Fibrillation: An Evidence-Based Consideration.非维生素K拮抗剂口服抗凝剂治疗非瓣膜性心房颤动患者的合适给药方案：基于证据的考量

Front Pharmacol. 2020 Aug 20;11:1293. doi: 10.3389/fphar.2020.01293. eCollection 2020.

Non-Vitamin K Antagonist Oral Anticoagulants Provide Less Adverse Renal Outcomes Than Warfarin In Non-Valvular Atrial Fibrillation: A Systematic Review and MetaAnalysis.非维生素 K 拮抗剂口服抗凝剂在非瓣膜性心房颤动中的肾脏不良结局少于华法林：系统评价和荟萃分析。

J Am Heart Assoc. 2021 Apr 6;10(7):e019609. doi: 10.1161/JAHA.120.019609. Epub 2021 Mar 17.

Vitamin K and non-vitamin K antagonist oral anticoagulants for non-valvular atrial fibrillation in real-life.维生素K与非维生素K拮抗剂口服抗凝药用于非瓣膜性心房颤动的真实世界研究

Eur J Intern Med. 2016 Sep;33:42-6. doi: 10.1016/j.ejim.2016.06.022. Epub 2016 Jul 6.

Stroke prevention strategies in patients with atrial fibrillation and heart valve abnormalities: perceptions of 'valvular' atrial fibrillation: results of the European Heart Rhythm Association Survey.心房颤动合并心脏瓣膜异常患者的卒中预防策略：对“瓣膜性”心房颤动的认知：欧洲心律协会调查结果

Europace. 2016 Oct;18(10):1593-1598. doi: 10.1093/europace/euw302.

Comparison of Renal Function Estimation Formulae for Dosing Direct Oral Anticoagulants in Patients with Atrial Fibrillation.用于心房颤动患者直接口服抗凝剂给药的肾功能估算公式比较

J Clin Med. 2019 Nov 21;8(12):2034. doi: 10.3390/jcm8122034.

The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation.2018 年欧洲心脏病学会关于非维生素 K 拮抗剂口服抗凝剂在心房颤动患者中应用的实用指南。

Eur Heart J. 2018 Apr 21;39(16):1330-1393. doi: 10.1093/eurheartj/ehy136.

Dosing issues with non-vitamin K antagonist oral anticoagulants for the treatment of non-valvular atrial fibrillation: Why we should not underdose our patients.非维生素 K 拮抗剂口服抗凝剂治疗非瓣膜性心房颤动的剂量问题：我们为何不应给患者低剂量治疗。

Arch Cardiovasc Dis. 2018 Feb;111(2):85-94. doi: 10.1016/j.acvd.2017.04.008. Epub 2017 Oct 2.

Non-valvular atrial fibrillation: potential clinical implications of the heterogeneous definitions used in trials on new oral anticoagulants.非瓣膜性心房颤动：新型口服抗凝剂试验中使用的异质性定义的潜在临床意义。

J Cardiovasc Med (Hagerstown). 2015 Jul;16(7):491-6. doi: 10.2459/JCM.0000000000000236.

本文引用的文献

Different Renal Function Equations and Dosing of Direct Oral Anticoagulants in Atrial Fibrillation.不同的肾功能方程与心房颤动中直接口服抗凝剂的给药剂量

JACC Asia. 2022 Feb 1;2(1):46-58. doi: 10.1016/j.jacasi.2021.11.006. eCollection 2022 Feb.

Should We Continue Assessing Glomerular Filtration Rate with the Cockroft-Gault Formula in NOAC-Treated Patients? The Magnitude of the Problem.在接受新型口服抗凝药（NOAC）治疗的患者中，我们是否应该继续使用 Cockcroft-Gault 公式评估肾小球滤过率？问题的严重程度。

J Clin Med. 2020 Jun 17;9(6):1893. doi: 10.3390/jcm9061893.

[Anticoagulation in patients with non-valvular atrial fibrillation (nvAF) and chronic kidney disease (CKD)].非瓣膜性心房颤动（nvAF）合并慢性肾脏病（CKD）患者的抗凝治疗

Dtsch Med Wochenschr. 2019 Nov;144(23):1642-1649. doi: 10.1055/a-1008-5548. Epub 2019 Nov 21.

Outcomes associated with non-recommended dosing of rivaroxaban: results from the XANTUS study.与利伐沙班非推荐剂量相关的结局：来自 XANTUS 研究的结果。

Eur Heart J Cardiovasc Pharmacother. 2019 Apr 1;5(2):70-79. doi: 10.1093/ehjcvp/pvy041.

The Comparison of Inappropriate-Low-Doses Use among 4 Direct Oral Anticoagulants in Patients with Atrial Fibrillation: From the Database of a Single-Center Registry.心房颤动患者中4种直接口服抗凝剂不适当低剂量使用情况的比较：来自单中心注册数据库

J Stroke Cerebrovasc Dis. 2018 Nov;27(11):3280-3288. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.028. Epub 2018 Aug 16.

Variability in Non-Vitamin K Antagonist Oral Anticoagulants Dose Adjustment in Atrial Fibrillation Patients With Renal Dysfunction: The Influence of Renal Function Estimation Formulae.肾功能障碍的心房颤动患者中非维生素 K 拮抗剂口服抗凝剂剂量调整的变异性：肾功能估计公式的影响。

Can J Cardiol. 2018 Aug;34(8):1010-1018. doi: 10.1016/j.cjca.2018.04.019. Epub 2018 Apr 25.

Eur Heart J. 2018 Apr 21;39(16):1330-1393. doi: 10.1093/eurheartj/ehy136.

Off-Label Dosing of Non-Vitamin K Antagonist Oral Anticoagulants and Adverse Outcomes: The ORBIT-AF II Registry.非维生素 K 拮抗剂口服抗凝剂的标签外剂量与不良结局：ORBIT-AF II 注册研究。

J Am Coll Cardiol. 2016 Dec 20;68(24):2597-2604. doi: 10.1016/j.jacc.2016.09.966.

Creatinine Clearance Is Not Equal to Glomerular Filtration Rate and Cockcroft-Gault Equation Is Not Equal to CKD-EPI Collaboration Equation.肌酐清除率不等于肾小球滤过率，Cockcroft-Gault 方程不等于 CKD-EPI 协作方程。

Am J Med. 2016 Dec;129(12):1259-1263. doi: 10.1016/j.amjmed.2016.08.019. Epub 2016 Sep 6.

2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS.2016年欧洲心脏病学会（ESC）与欧洲心胸外科学会（EACTS）合作制定的心房颤动管理指南。

Eur Heart J. 2016 Oct 7;37(38):2893-2962. doi: 10.1093/eurheartj/ehw210. Epub 2016 Aug 27.

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Impact of Renal Function Estimation Formulae on Use and Correct Dosing of NOACs in Patients with Non-valvular Atrial Fibrillation in Real Life in Germany.

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