Hirai Aya, Sato Kaito, Hoshi Toru, Aoyagi Takao
Department of Materials and Applied Chemistry, Graduate School of Science and Technology, Nihon University, 1-8-14, Kanda-Surugadai, Tokyo 101-8308, Japan.
Department of Materials and Applied Chemistry, College of Science and Technology, Nihon University, 1-8-14, Kanda-Surugadai, Tokyo 101-8308, Japan.
Gels. 2024 Nov 8;10(11):723. doi: 10.3390/gels10110723.
To reduce the risk of adsorption of granular activated carbon (AC) in the gastrointestinal tract, we successfully prepared a hollow-type spherical bacterial cellulose gel encapsulated with AC (ACEG) and evaluated its pH tolerance and adsorption capacity. The bacterial cellulose gel membrane of ACEG features a three-dimensional mesh structure of cellulose fibers, allowing the selective permeation of substances based on their size. In this study, the preparation method of ACEGs was investigated, and the indole saturation adsorption capacity of the obtained gel was measured. We modified the gel culture nucleus gel from calcium alginate gel to agar gel, facilitating the encapsulation of previously challenging particles. The new preparation method used sodium hydroxide solution for sterilization and dissolution to remove the debris of , which was feared to remain in the bacterial cellulose membrane. This treatment was also confirmed to have no effect on the adsorption capacity of the AC powder. Therefore, this new preparation method is expected not only to improve the performance of ACEGs but also to be applied to a wide range of adsorbent-encapsulated hollow-type bacterial cellulose gels.
为降低颗粒活性炭（AC）在胃肠道中的吸附风险，我们成功制备了一种包裹有AC的中空型球形细菌纤维素凝胶（ACEG），并评估了其耐pH值性能和吸附能力。ACEG的细菌纤维素凝胶膜具有纤维素纤维的三维网状结构，可根据物质大小实现选择性渗透。在本研究中，对ACEGs的制备方法进行了研究，并测定了所得凝胶对吲哚的饱和吸附容量。我们将凝胶培养核凝胶从海藻酸钙凝胶改为琼脂凝胶，便于对先前具有挑战性的颗粒进行包封。新的制备方法使用氢氧化钠溶液进行灭菌和溶解，以去除担心残留在细菌纤维素膜中的杂质。该处理也被证实对AC粉末的吸附能力没有影响。因此，这种新的制备方法不仅有望提高ACEGs的性能，还可应用于广泛的吸附剂包封中空型细菌纤维素凝胶。
