Phothikun Amarit, Kanokkavinvong Nutthayuth, Nawarawong Weerachai, Taksaudom Noppon, Woragidpoonpol Surin
Cardiovascular and Thoracic Surgery Unit, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Clinical Epidemiology and Clinical Statistic Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Aorta (Stamford). 2024 Jun;12(3):60-69. doi: 10.1055/s-0044-1795129. Epub 2024 Nov 26.
Aggressive surgical methods for acute type A aortic dissection (ATAD) can cause extended operating times and postoperative complications. less extensive techniques may increase the risk of needing further aortic reintervention. To prevent the need for extensive aortic arch surgery and subsequent re-sternotomy, hemiarch replacement (HAR) with innominate artery (a.) translocation is performed to create a suitable proximal landing zone for future endovascular repair.
Retrospective study of 112 patients with ATAD who underwent aortic surgery from January 2009 to December 2020. Forty-one patients underwent HAR with innominate artery translocation, 16 underwent total arch replacement (TAR), and 55 underwent only HAR. Multivariable Cox regression and logistic regression analyses were used to study the outcomes and risk factors.
The TAR group had a higher incidence of postoperative acute kidney injury. The overall mortality rate of the TAR group was 25%, compared with 20% in the HAR group and 14.6% in the translocation group. The 5-year overall survival rates for the groups were 81.9%, 75.0%, and 77.7%, respectively. False lumen thrombosis at the aortic arch and descending aorta level were factors associated with reduced mortality in both univariable and multivariable analyses. The translocation group had a significantly higher reintervention rate of 41.5% compared with the TAR and HAR groups, with rates of 31.3% and 16.4%, respectively. The median reintervention time for the translocation group was 4.72 years.
Despite the innominate translocation technique having a higher reintervention rate, it had similar mortality outcomes to HAR and TAR. Thus, it could be a more convenient option for reintervention, including creating a proximal landing zone, which could benefit patients needing endovascular repair.
治疗急性A型主动脉夹层(ATAD)的激进手术方法可能会导致手术时间延长和术后并发症。不太激进的技术可能会增加再次进行主动脉干预的风险。为避免进行广泛的主动脉弓手术及随后的再次开胸手术,可采用带无名动脉移位的半弓置换术(HAR)来创建合适的近端锚定区,以便未来进行血管腔内修复。
对2009年1月至2020年12月期间接受主动脉手术的112例ATAD患者进行回顾性研究。41例患者接受了带无名动脉移位的HAR,16例接受了全弓置换术(TAR),55例仅接受了HAR。采用多变量Cox回归和逻辑回归分析来研究结果和风险因素。
TAR组术后急性肾损伤的发生率较高。TAR组的总死亡率为25%,而HAR组为20%,移位组为14.6%。三组的5年总生存率分别为81.9%、75.0%和77.7%。在单变量和多变量分析中,主动脉弓和降主动脉水平的假腔血栓形成都是与死亡率降低相关的因素。移位组的再次干预率显著高于TAR组和HAR组,分别为41.5%、31.3%和16.4%。移位组再次干预的中位时间为4.72年。
尽管无名动脉移位技术的再次干预率较高,但其死亡率结果与HAR和TAR相似。因此,它可能是再次干预的更便利选择,包括创建近端锚定区,这可能使需要血管腔内修复的患者受益。