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Heating Efficiency of Different Magnetotactic Bacterial Species: Influence of Magnetosome Morphology and Chain Arrangement.

作者信息

Villanueva Danny, G Gubieda Alicia, Gandarias Lucía, Abad Díaz de Cerio Ana, Orue Iñaki, Ángel García José, de Cos David, Alonso Javier, Fdez-Gubieda M Luisa

机构信息

Departamento de Electricidad y Electrónica, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.

Departamento de Inmunología, Microbiología y Parasitología, Universidad del País Vasco (UPV/EHU), 48940 Leioa, Spain.

出版信息

ACS Appl Mater Interfaces. 2024 Dec 11;16(49):67216-67224. doi: 10.1021/acsami.4c13152. Epub 2024 Nov 26.


DOI:10.1021/acsami.4c13152
PMID:39592122
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11647901/
Abstract

Magnetotactic bacteria have been proposed as ideal biological nanorobots due to the presence of an intracellular chain of magnetic nanoparticles (MNPs), which allows them to be guided and controlled by external magnetic fields and provides them with theragnostic capabilities intrinsic to magnetic nanoparticles, such as magnetic hyperthermia for cancer treatment. Here, we study three different bacterial species, (MSR-1), (AMB-1), and (MV-1), which synthesize magnetite nanoparticles with different morphologies and chain arrangements. We analyzed the impact of these parameters on the effective magnetic anisotropy, , and the heating capacity or Specific Absorption Rate, SAR, under alternating magnetic fields. SAR values have been obtained from the area of experimental AC hysteresis loops, while has been determined from simulations of AC hysteresis loops using a dynamic Stoner-Wohlfarth model. The results demonstrate a clear relationship between the effective magnetic anisotropy and the heating efficiency of bacteria. As the value increases, the saturated SAR values are higher; however, the threshold magnetic field required to observe a SAR response simultaneously increases. This factor is crucial to choose a bacterial species as the optimal hyperthermia agent.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/4a344dfc86c2/am4c13152_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/8ccf349d2ebd/am4c13152_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/1bbf75d1da17/am4c13152_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/917c8a7d41b2/am4c13152_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/670b9040db2e/am4c13152_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/4a344dfc86c2/am4c13152_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/8ccf349d2ebd/am4c13152_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/1bbf75d1da17/am4c13152_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/917c8a7d41b2/am4c13152_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/670b9040db2e/am4c13152_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5b36/11647901/4a344dfc86c2/am4c13152_0005.jpg

相似文献

[1]
Heating Efficiency of Different Magnetotactic Bacterial Species: Influence of Magnetosome Morphology and Chain Arrangement.

ACS Appl Mater Interfaces. 2024-12-11

[2]
Tuning the Magnetic Response of Magnetospirillum magneticum by Changing the Culture Medium: A Straightforward Approach to Improve Their Hyperthermia Efficiency.

ACS Appl Mater Interfaces. 2023-1-11

[3]
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J Nanobiotechnology. 2019-12-23

[4]
Exploring the Complex Interplay of Anisotropies in Magnetosomes of Magnetotactic Bacteria.

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[5]
Preparation of chains of magnetosomes, isolated from Magnetospirillum magneticum strain AMB-1 magnetotactic bacteria, yielding efficient treatment of tumors using magnetic hyperthermia.

Int J Pharm. 2012-6-12

[6]
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[7]
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[8]
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[9]
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[10]
Structural purity of magnetite nanoparticles in magnetotactic bacteria.

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引用本文的文献

[1]
Exploring the Complex Interplay of Anisotropies in Magnetosomes of Magnetotactic Bacteria.

ACS Omega. 2025-4-14

本文引用的文献

[1]
Understanding magnetic hyperthermia performance within the "Brezovich criterion": beyond the uniaxial anisotropy description.

Nanoscale. 2024-8-7

[2]
Experimental analysis of diverse actin-like proteins from various magnetotactic bacteria by functional expression in .

mBio. 2023-10-31

[3]
Oncolytic virotherapy: basic principles, recent advances and future directions.

Signal Transduct Target Ther. 2023-4-11

[4]
Therapy with oncolytic viruses: progress and challenges.

Nat Rev Clin Oncol. 2023-3

[5]
Multifunctional nanocarriers of FeO@PLA-PEG/curcumin for MRI, magnetic hyperthermia and drug delivery.

Nanomedicine (Lond). 2022-9

[6]
Magnetotactic Bacteria-Based Drug-Loaded Micromotors for Highly Efficient Magnetic and Biological Double-Targeted Tumor Therapy.

ACS Appl Mater Interfaces. 2023-1-18

[7]
Tuning the Magnetic Response of Magnetospirillum magneticum by Changing the Culture Medium: A Straightforward Approach to Improve Their Hyperthermia Efficiency.

ACS Appl Mater Interfaces. 2023-1-11

[8]
Hybrid magnetic nanoparticles as efficient nanoheaters in biomedical applications.

Nanoscale Adv. 2021-1-15

[9]
Time-dependent AC magnetometry and chain formation in magnetite: the influence of particle size, initial temperature and the shortening of the relaxation time by the applied field.

Nanoscale Adv. 2021-8-13

[10]
Magnetic Anisotropy of Individual Nanomagnets Embedded in Biological Systems Determined by Axi-asymmetric X-ray Transmission Microscopy.

ACS Nano. 2022-5-24

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